ReviewJournal of biosciences2020
Axonal cytomechanics in neuronal development.
Review in Journal of biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Review
- Neuromechanobiology: Bridging Mechanobiology and Neuroscience Through Evidence and Open Questions.Cells · 2026Review
- Emerging Trends: Neurofilament Biomarkers in Precision Neurology.Neurochemical research · 2024Review
- Neurofilaments as biomarkers in neurological disorders - towards clinical application.Nature reviews. Neurology · 2024Review
- The role of mechanics in axonal stability and development.Seminars in cell & developmental biology · 2023Review
- The 2022 Lady Estelle Wolfson lectureship on neurofilaments.Journal of neurochemistry · 2022Review
- Antagonistic Activities of Fmn2 and ADF Regulate Axonal F-Actin Patch Dynamics and the Initiation of Collateral Branching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Mathematical models of neuronal growth.Biomechanics and modeling in mechanobiology · 2022Review
- Magnetically-actuated microposts stimulate axon growth.Biophysical journal · 2022Article
- A Brief Review of In Vitro Models for Injury and Regeneration in the Peripheral Nervous System.International journal of molecular sciences · 2022Review
- Understanding, engineering, and modulating the growth of neural networks: An interdisciplinary approach.Biophysics reviews · 2021Review
- Manipulation of Axonal Outgrowth via Exogenous Low Forces.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For more than a century, mechanical forces have been predicted to govern many biological processes during development, both at the cellular level and in tissue homeostasis. The cytomechanics of the thin and highly extended neuronal axons have intrigued generations of biologists and biophysicists. However, our knowledge of the biophysics of neurite growth and development is far from complete. Due to its motile behavior and its importance in axonal pathfinding, the growth cone has received significant attention. A considerable amount of information is now available on the spatiotemporal regulation of biochemical signaling and remodeling of the growth cone cytoskeleton. However, the cytoskeletal organization and dynamics in the axonal shaft were poorly explored until recently. Driven by advances in microscopy, there has been a surge of interest in the axonal cytoskeleton in the last few years. A major emerging area of investigation is the relationship between the axonal cytoskeleton and the diverse mechanobiological responses of neurons. This review attempts to summarize our current understanding of the axonal cytoskeleton and its critical role in governing axonal mechanics in the context of neuronal development.
Indexed as
Identifiers
32385223W3026720888What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.