ReviewRMD open2020
Management of Fatigue in Rheumatoid Arthritis.
Review in RMD open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 6 syntheses or guidelines pooled it, 125 citations in OpenAlex.
- Pooled it
- Investigating the Association Between Social Support and Quality of Life in People With Rheumatoid Arthritis: A Systematic Review of the Literature.International journal of rheumatic diseases · 2025Pooled it
- Vaccination and rheumatoid arthritis: an updated systematic review and meta-analysis of data from 25,949,597 participants.BMC public health · 2025Pooled it
- Immunological Insights into the Causal Link Between Arthritis, Osteoarthritis, and Frailty: An Integrated Analytical Study.International journal of medical sciences · 2025Pooled it
- The effects of Tai Chi on physical function and safety in patients with rheumatoid arthritis: A systematic review and meta-analysis.Frontiers in physiology · 2023Pooled it
- Efficacy and Safety of Curcumin andFrontiers in immunology · 2022Pooled it
- Effectiveness of Yoga and Combined Exercise in Female With Rheumatoid Arthritis: Randomized Controlled Trial.Musculoskeletal care · 2026Trial
- The effect of photobiomodulation therapy on fatigue and behavioural status in patients with Hashimoto's thyroiditis.Lasers in medical science · 2026Trial
- Trial
- High-intensity exercise improves multidimensional fatigue and health-related quality of life in rheumatoid arthritis: a randomized controlled study.Arthritis research & therapy · 2025Trial
- Effects of a novel differential diagnosis aid for managing patients with unexplained fatigue in primary care: a prospective randomized, controlled, open and multicenter study in primary care.BMC primary care · 2025Trial
- The impact of tofacitinib on fatigue, sleep, and health-related quality of life in patients with rheumatoid arthritis: a post hoc analysis of data from Phase 3 trials.Arthritis research & therapy · 2022Trial
- Short-Interval Discordance Between Fatigue and Joint Counts in Rheumatoid Arthritis.International journal of rheumatic diseases · 2026Article
- Learning to live with RA as an unwelcome companion-patients' experiences after 1 to 2 years of DMARD treatment.EULAR rheumatology open · 2026Article
- Similar negative effects of fatigue on physical activity in persons with rheumatoid arthritis and healthy controls: results of a cross-sectional patient-control study.EULAR rheumatology open · 2026Article
- Ya Han Jie ameliorates adjuvant-induced arthritis by inhibiting the NF-κB/NETosis/inflammation axis.Chinese medicine · 2026Article
- Beyond Inflammation: Associations of Depression and Anxiety With Fatigue in Rheumatoid Arthritis.Cureus · 2026Article
- Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review).Experimental and therapeutic medicine · 2026Review
- Challenges, motivators and coping strategies of iron-folic acid tablets intake in the girls iron-folic acid tablet supplementation program in Wa municipality of Ghana.BMC nutrition · 2026Article
- Association of comorbid depressive and anxiety symptoms with cognitive impairment and dementia in Chinese elderly people.BMC psychiatry · 2026Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue in rheumatoid arthritis is highly prevalent. It is correlated only weakly with disease activity but more so with pain, mood, personality features, poor sleep, obesity and comorbidities. Fatigue can be measured by many standardised questionnaires and more easily with a Visual Analogue Scale or numeric rating scale. Most patients with RA have some fatigue, and at least one in six have severe fatigue. Chronic pain and depressed mood are also common in RA patients with significant fatigue. It affects function and quality of life and is worse on average in women. Evidence-based treatment for fatigue includes treatment of underlying disease activity (with on average modest improvement of fatigue), exercise programmes and supervised self-management programmes with cognitive-behavioural therapy, mindfulness and reinforcement (such as reminders). The specific programmes for exercise and behavioural interventions are not standardised. Some medications cause fatigue such as methotrexate. More research is needed to understand fatigue and how to treat this common complex symptom in RA that can be the worst symptom for some patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.