Evidence map›Paper›PMID 32385108›Full record

ArticleThe Journal of biological chemistry2020

Role of folding kinetics of secondary structures in telomeric G-overhangs in the regulation of telomere maintenance in

Katarina Jurikova, Martin Gajarsky, Mona Hajikazemi, Jozef Nosek, Katarina Prochazkova, Katrin Paeschke, Lukas Trantirek, Lubomir Tomaska

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Article
  6. Investigating the role of G-quadruplexes atMicrobial cell (Graz, Austria) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Telomere Replication: Solving Multiple End Replication Problems.Frontiers in cell and developmental biology · 2021
    Review
  12. G-Quadruplexes at Telomeres: Friend or Foe?Molecules (Basel, Switzerland) · 2020
    Review
  13. Review
  14. Fundamentals of G-quadruplex biology.Annual reports in medicinal chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Katarina JurikovaDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia.
Martin GajarskyCentral European Institute of Technology, Masaryk University, Brno, Czech Republic.
Mona HajikazemiDepartment of Oncology, Hematology and Rheumatology, University Hospital Bonn, Bonn, Germany.
Jozef NosekDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia.
Katarina ProchazkovaDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia.
Katrin PaeschkeDepartment of Oncology, Hematology and Rheumatology, University Hospital Bonn, Bonn, Germany.
Lukas TrantirekCentral European Institute of Technology, Masaryk University, Brno, Czech Republic; Institute of Biophysics, Czech Academy of Sciences, Brno, Czech Republic. Electronic address: lukas.trantirek@ceitec.muni.cz.
Lubomir TomaskaDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, Bratislava, Slovakia. Electronic address: lubomir.tomaska@uniba.sk.
Comenius University Bratislava · SKCentral European Institute of Technology · CZUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ends of eukaryotic chromosomes typically contain a 3' ssDNA G-rich protrusion (G-overhang). This overhang must be protected against detrimental activities of nucleases and of the DNA damage response machinery and participates in the regulation of telomerase, a ribonucleoprotein complex that maintains telomere integrity. These functions are mediated by DNA-binding proteins, such as Cdc13 in

Indexed as

DNADNA-Binding ProteinsDNA, Single-StrandedElectrophoretic Mobility Shift AssayG-QuadruplexesKineticsNucleic Acid ConformationOligonucleotidesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTelomeraseTelomereTelomere-Binding ProteinsTelomere HomeostasisCdc13 protein, S cerevisiaeDNADNA-Binding ProteinsDNA, Single-StrandedOligonucleotidesSaccharomyces cerevisiae ProteinsTelomeraseTelomere-Binding ProteinsCdc13cell cyclefolding kineticsG-hairpinG-quadruplexSaccharomyces cerevisiaetelomerasetelomere

Identifiers

PMID32385108
PMCPMC7335780
OpenAlexW3021679129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.