Evidence map›Paper›PMID 32385059›Full record

Observational studyBMJ open2020

Chest radiograph findings in children aged 2-59 months hospitalised with community-acquired pneumonia, prior to the introduction of pneumococcal conjugate vaccine in India: a prospective multisite observational study.

Shally Awasthi, Tuhina Rastogi, Neha Mishra, Abhishek Chauhan, Namita Mohindra, Ram Chandra Shukla, Monika Agarwal, Chandra Mani Pandey, Neera Kohli, Cap Study Group

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Shally AwasthiDepartment of Pediatrics, King George's Medical University, Lucknow, India shally07@gmail.com.ORCID 0000-0003-1254-9802
Tuhina RastogiDepartment of Pediatrics, King George's Medical University, Lucknow, India.
Neha MishraDepartment of Pediatrics, King George's Medical University, Lucknow, India.
Abhishek ChauhanDepartment of Radio-diagnosis, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Namita MohindraDepartment of Radio-diagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Ram Chandra ShuklaDepartment of Radio-diagnosis, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Monika AgarwalDepartment of Community Medicine and Public Health, King George's Medical University, Lucknow, India.
Chandra Mani PandeyDepartment of Biostatistics & Health Informatics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Neera KohliDepartment of Radio-diagnosis, King George's Medical University, Lucknow, India.
Cap Study GroupCAP Study Group, Lucknow, India.
King George's Medical University · INSanjay Gandhi Post Graduate Institute of Medical Sciences · INDr. Ram Manohar Lohia Institute of Medical Sciences · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe current study was a hospital-based surveillance of cases hospitalised with WHO-defined community-acquired pneumonia in children aged 2-59 months, to assess the radiological abnormalities in chest X-rays and to identify the demographic and clinical correlates of specific radiological abnormalities, in residents of prespecified districts of Uttar Pradesh and Bihar, India.

designProspective, active, hospital-based surveillance.

settingMultisite study conducted in a network of 117 secondary/tertiary care hospitals in four districts of Uttar Pradesh and Bihar, India.

participantsIncluded were children aged 2-59 months, hospitalised with community-acquired pneumonia, residing in the project district, with duration of illness <14 days and who had not been hospitalised elsewhere for this episode nor had been recruited previously.

main outcome measureConcordant radiological abnormalities in the chest X-rays.

resultsFrom January 2015 to April 2017, 3214 cases were recruited and in 99.40% (3195/3214) chest X-rays were available, among which 88.54% (2829/3195) were interpretable. Relevant radiological abnormalities were found in 34.53% (977/2829, 95% CI 32.78 to 36.28). These were primary end point pneumonia alone or with other infiltrates in 22.44% (635/2829, 95% CI 20.90% to 23.98%) and other infiltrates in 12.09% (342/2829; 95% CI 10.88% to 13.29%). There was a statistically significant interdistrict variation in radiological abnormalities. Statistically significantly higher proportion of abnormal chest X-rays were found in girls, those with weight-for-age z-score ≤-3SD, longer duration of fever, pallor and with exposure to biomass fuel.

conclusionsAmong hospitalised cases of community-acquired pneumonia, almost one-third children had abnormal chest radiographs, which were higher in females, malnourished children and those with longer illnesses; and an intra-district variation was observed.

Indexed as

Community-Acquired InfectionsPneumoniaPneumonia, PneumococcalAdolescentAdultChildChild, PreschoolFemaleHumansIndiaInfantMaleMiddle AgedProspective StudiesVaccines, ConjugateYoung AdultVaccines, Conjugatechest radiographshospitalised community-acquired pneumoniaIndiaStreptococcus pneumoniaeunder-5

Identifiers

PMID32385059
PMCPMC7228527
OpenAlexW3021250421

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.