ArticleBMC plant biology2020
Coordination between GROWTH-REGULATING FACTOR1 and GRF-INTERACTING FACTOR1 plays a key role in regulating leaf growth in rice.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 62 citations in OpenAlex.
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- Genome-wide association study (GWAS) and transcriptome analysis reveal new candidate genes for leaf size in alfalfa.BMC plant biology · 2026Article
- Loci and natural alleles for leaf length and width revealed by a genome wide association study in adzuki bean.BMC plant biology · 2025Article
- Phenotypic Identification and Fine-Mapping of the Rice Narrow-Leaf MutantPlants (Basel, Switzerland) · 2025Article
- Identification and characterization of the miR396f-GRF10 module in phase transition of Lilium.Planta · 2025Article
- Unraveling the Multilayered Regulatory Networks of miRNAs and PhasiRNAs inPlants (Basel, Switzerland) · 2025Article
- Gibberellins: extending the Green Revolution.Journal of experimental botany · 2025Review
- OsLC1, a transaldolase, regulates cell patterning and leaf morphology through modulation of secondary metabolism.Plant biotechnology journal · 2025Article
- Genome-wide identification and comparative evolution of 14-3-3 gene family members in five Brassicaceae species.BMC genomics · 2025Article
- Identification and functional analysis of growth- regulating factors involved in abiotic stress response inFrontiers in plant science · 2025Article
- Genetic variations associated with adaptation in Acrocomia palms: A comparative study across the Neotropics for crop improvement.PloS one · 2025Article
- Escaping endogenous miRNA post-transcriptional silencing ofFrontiers in plant science · 2025Article
- Variation in WIDTH OF LEAF AND GRAIN contributes to grain and leaf size by controlling LARGE2 stability in rice.The Plant cell · 2024Article
- Genome-wide identification and expression profiling of growth‑regulating factor (GRF) and GRF‑interacting factor (GIF) gene families in chickpea and pigeonpea.Scientific reports · 2024Article
- RNA-Seq Reveals That Multiple Pathways Are Involved in Tuber Expansion in Tiger Nuts (International journal of molecular sciences · 2024Article
- Article
- Advancements in Rice Leaf Development Research.Plants (Basel, Switzerland) · 2024Review
- Genome-wide molecular evolution analysis of the GRF and GIF gene families in Plantae (Archaeplastida).BMC genomics · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe interactions between Growth-regulating factors (GRFs) and GRF-Interacting Factors (GIFs) have been well demonstrated but it remains unclear whether different combinations of GRF and GIF play distinctive roles in the pathway downstream of the complex.
resultsHere we showed that OsGRF1 and OsGIF1 synergistically regulate leaf growth in rice. The expression of OsGIF1 emerged in all tissues with much higher level while that of OsGRF1 appeared preferentially only in the stem tips containing shoot apical meristem (SAM) and younger leaves containing leaf primordium. Overexpression of an OsmiR396-resistant version of mOsGRF1 resulted in expanded leaves due to increased cell proliferation while knockdown of OsGRF1 displayed an opposite phenotype. Overexpression of OsGIF1 did not exhibit new phenotype while knockdown lines displayed pleiotropic growth defects including shrunken leaves. The crossed lines of mOsGRF1 overexpression and OsGIF1 knockdown still exhibited shrunk leaves, indicating that OsGIF1 is indispensable in leaf growth regulated by OsGRF1. The expression of OsGRF1 could be upregulated by gibberellins (GAs) and downregulated by various stresses while that of OsGIF1 could not.
conclusionOur results suggest that OsGIF1 is in an excessive expression in various tissues and play roles in various aspects of growth while OsGRF1 may specifically involve in leaf growth through titrating OsGIF1. Both internal and external conditions impacting leaf growth are likely via way of regulating the expression of OsGRF1.
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