Evidence map›Paper›PMID 32384813›Full record

ReviewMaterials (Basel, Switzerland)2020

Electrospun Nano-Fibers for Biomedical and Tissue Engineering Applications: A Comprehensive Review.

Shokoh Parham, Anousheh Zargar Kharazi, Hamid Reza Bakhsheshi-Rad, Hamid Ghayour, Ahmad Fauzi Ismail, Hadi Nur, Filippo Berto

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shokoh ParhamBiomaterials Nanotechnology and Tissue Engineering Faculty, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan 8174673461, Iran.
Anousheh Zargar KharaziBiomaterials Nanotechnology and Tissue Engineering Faculty, School of Advanced Medical Technology, Isfahan University of Medical Sciences, Isfahan 8174673461, Iran.
Hamid Reza Bakhsheshi-RadAdvanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Hamid GhayourAdvanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Ahmad Fauzi IsmailAdvanced Membrane Technology Research Center (AMTEC), Universiti Teknologi Malaysia, Skudai, Johor Bahru, Johor 81310, Malaysia.
Hadi NurCentre for Sustainable Nanomaterials, Ibnu Sina Institute for Scientific and Industrial Research, Universiti Teknologi Malaysia, UTM Skudai, Johor 81310, Malaysia.
Filippo BertoDepartment of Mechanical and Industrial Engineering, Norwegian University of Science and Technology, 7491 Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical nano-fibers have attracted widespread attention from researchers for reasons such as adaptability of the electro-spinning process and ease of production. As a flexible method for fabricating nano-fibers, electro-spinning is extensively used. An electro-spinning unit is composed of a pump or syringe, a high voltage current supplier, a metal plate collector and a spinneret. Optimization of the attained nano-fibers is undertaken through manipulation of the variables of the process and formulation, including concentration, viscosity, molecular mass, and physical phenomenon, as well as the environmental parameters including temperature and humidity. The nano-fibers achieved by electro-spinning can be utilized for drug loading. The mixing of two or more medicines can be performed via electro-spinning. Facilitation or inhibition of the burst release of a drug can be achieved by the use of the electro-spinning approach. This potential is anticipated to facilitate progression in applications of drug release modification and tissue engineering (TE). The present review aims to focus on electro-spinning, optimization parameters, pharmacological applications, biological characteristics, and in vivo analyses of the electro-spun nano-fibers. Furthermore, current developments and upcoming investigation directions are outlined for the advancement of electro-spun nano-fibers for TE. Moreover, the possible applications, complications and future developments of these nano-fibers are summarized in detail.

Indexed as

drug deliveryelectrospinningfabricationnano-fibersparameters effectwound dressing

Identifiers

PMID32384813
PMCPMC7254207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.