Evidence map›Paper›PMID 32384749›Full record

ArticleInternational journal of environmental research and public health2020

Effect of Kelulut Honey on the Cellular Dynamics of TGFβ-Induced Epithelial to Mesenchymal Transition in Primary Human Keratinocytes.

Abid Nordin, Shiplu Roy Chowdhury, Aminuddin Bin Saim, Ruszymah Bt Hj Idrus

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Abid NordinDepartment of Physiology, Faculty of Medicine, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-9717-6691
Shiplu Roy ChowdhuryTissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Kuala Lumpur 56000, Malaysia.
Aminuddin Bin SaimEar, Nose & Throat Consultant Clinic, Ampang Puteri Specialist Hospital, Ampang, Selangor 68000, Malaysia.
Ruszymah Bt Hj IdrusDepartment of Physiology, Faculty of Medicine, Cheras, Kuala Lumpur 56000, Malaysia.
University Kebangsaan Malaysia Medical Centre · MYKPJ Ampang Puteri Specialist Hospital · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over-induction of epithelial to mesenchymal transition (EMT) by tumor growth factor beta (TGFβ) in keratinocytes is a key feature in keloid scar. The present work seeks to investigate the effect of Kelulut honey (KH) on TGFβ-induced EMT in human primary keratinocytes. Image analysis of the real time observation of TGFβ-induced keratinocytes revealed a faster wound closure and individual migration velocity compared to the untreated control. TGFβ-induced keratinocytes also have reduced circularity and display a classic EMT protein expression. Treatment of 0.0015% (

Indexed as

Epithelial-Mesenchymal TransitionWound HealingCell MovementHoneyHumansKeratinocytesMaleTransforming Growth Factor betaTransforming Growth Factor betacell morphologyhoneykeloid scarmigrationscratch assaywound healing

Identifiers

PMID32384749
PMCPMC7246951
OpenAlexW3021371095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.