ArticlePloS one2020
Physical activity and risk of cardiovascular disease by weight status among U.S adults.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- The Benefits of Physical Activity for People with Obesity, Independent of Weight Loss: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Cost-Effectiveness of Two Iterations of a Community-Based Cardiovascular Disease Prevention Intervention.Obesity (Silver Spring, Md.) · 2026Trial
- Adaptive Goals and Reinforcement Timing to Increase Physical Activity in Adults: A Factorial Randomized Trial.American journal of preventive medicine · 2022Trial
- Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant-Based Therapies: A Narrative Review.Health science reports · 2026Article
- Physical activity among active-duty US military servicemembers with overweight and obesity.BMC public health · 2026Article
- Prospective Associations of Obesity and Obesity Severity With 9 Cardiovascular Outcomes: The Cross-Cohort Collaboration.Circulation · 2026Article
- The Interaction of Health Behaviors and Cardiovascular Diseases: Investigating Morbidity Risks of Disparities in U.S. Adults.Healthcare (Basel, Switzerland) · 2025Article
- Obesity and Exercise: New Insights and Perspectives.Endocrine reviews · 2025Review
- Eating disorders, nutrient intake, and cardiometabolic risks: a cross-sectional study in Turkish adults.BMC public health · 2025Article
- Physical activity, cardiovascular disease, and mortality across obesity levels.The EPMA journal · 2025Article
- Psychometric evaluation of the exercise-related cognitive errors questionnaire among Chinese emerging adults.Frontiers in psychology · 2025Article
- Interactive Relations of Body Mass Index, Cardiorespiratory Fitness, and Sex to Cognitive Function in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Association of weight loss strategies with all-cause and specific-cause mortality: a prospective cohort study.BMC public health · 2024Article
- Prevalence and Factors Related to Physical Activity in Spanish Adults with Obesity and Overweight: Analysis of the European Health Surveys for the Years 2014 and 2020.Healthcare (Basel, Switzerland) · 2024Article
- Addressing differences in cancer: a framework for synergistic programming in cancer prevention and control.Research square · 2024Article
- Influence of dietary and lifestyle factors on levels of inflammatory markers (IL-6, IFN-γ and TNF-α) in obese subjects.Central-European journal of immunology · 2024Article
- Article
- Impact of modifiable risk factors on prediction of 10-year cardiovascular disease utilizing framingham risk score in Southwest Iran.BMC cardiovascular disorders · 2023Article
- Obesity and the risk of cardiometabolic diseases.Nature reviews. Cardiology · 2023Review
- The Effects of Obesity on the Inflammatory, Cardiovascular, and Neurobiological Responses to Exercise in Older Adults.Biology · 2023Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe sought to determine whether the association between physical activity and 10-year cardiovascular disease (CVD) risk varies among normal weight, overweight, and obese adults in a nationally-representative sample of the United States.
methodsData were from the National Health and Nutrition Examination Survey 2007-2016. A subset of 22,476 participants aged 30-64 years was included with no CVD history. Physical activity level was self-reported and stratified into sedentary (0 min/week), inactive (1-149 mins/week), or active (≥150 mins/week) of moderate or vigorous activities. Framingham risk scores were classified as low/intermediate (<20%) or high 10-year CVD risk (≥20%).
resultsThe average age of the population was 45.9 years, 52.3% were female, 33.6% were overweight (BMI 25.0-29.9kg/m2), and 35.7% were obese (BMI≥30kg/m2). Individuals who were overweight and obese had a higher 10-year CVD risk compared to those with normal weight (9.5 vs. 10.1 vs. 6.3%, P<0.001). The association of physical activity and high 10-year CVD risk differed by weight status. Among overweight and obese adults, individuals engaged in any physical activity had lower odds ofhigh 10-year CVD risk compared to sedentary individuals (overweight: OR active = 0.48, 95% CI: 0.36-0.64; OR inactive = 0.53, 95% CI: 0.45-0.86; obese: OR active = 0.50, 95% CI: 0.37-0.68; OR inactive = 0.66, 95% CI: 0.49-0.89). Among normal weight adults, individuals who were physically active had lower odds of high 10-year CVD risk (OR = 0.59, 95% CI: 0.28-0.87). When compared the joint effects of physical activity level and weight status, physical activity was associated with a larger magnitude of reduced odds of 10-year CVD risk than weight status.
conclusionParticipation in any level of physical activity is associated with a lower 10-year CVD risk for overweight and obese adults. Future studies are needed to identify effective modes and doses of exercise that offer optimal CVD benefits for populations with different weight statuses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.