Evidence map›Paper›PMID 32384078›Full record

ArticlePLoS neglected tropical diseases2020

Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study.

Rui Huang, Li Zhu, Leyang Xue, Longgen Liu, Xuebing Yan, Jian Wang, Biao Zhang, Tianmin Xu, Fang Ji, Yun Zhao and 19 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 33 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 33 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 33 syntheses or guidelines pooled it, 264 citations in OpenAlex.

  1. Obesity as an independent risk factor for COVID-19 severity and mortality.The Cochrane database of systematic reviews · 2023
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  6. Prevalence and prognosis of otorhinolaryngological symptoms in patients with COVID-19: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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  15. Outcomes of COVID-19 Complications and their Possibilities as Potential Triggers of Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
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  17. Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
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81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 10 institutions in 1 country.

Rui HuangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Li ZhuDepartment of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-0953-5912
Leyang XueDepartment of Critical Medicine, Huai'an No. 4 People's Hospital, Huai'an, China.
Longgen LiuDepartment of Infectious Diseases, The Third People's Hospital of Changzhou, Changzhou, China.
Xuebing YanDepartment of Infectious Diseases, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Jian WangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Biao ZhangDepartment of Quality Control Office, Huai'an No. 4 People's Hospital, Huai'an, China.
Tianmin XuDepartment of Infectious Diseases, The Third People's Hospital of Changzhou, Changzhou, China.
Fang JiDepartment of Infectious Diseases, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yun ZhaoDepartment of Infectious Diseases, The Third People's Hospital of Yangzhou, Yangzhou, China.
Juan ChengDepartment of Infectious Diseases, Yancheng Second People's Hospital, Yancheng, China.
Yinling WangDepartment of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China.
Huaping ShaoDepartment of Infectious Diseases, The People's Hospital of Suqian, Suqian, China.
Shuqin HongNursing Department, Huai'an No. 4 People's Hospital, Huai'an, China.
Qi CaoDepartment of Infectious Diseases, The Third People's Hospital of Changzhou, Changzhou, China.
Chunyang LiDepartment of Infectious Diseases, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xiang-An ZhaoDepartment of Gastroenterology, Northern Jiangsu People's Hospital, Clinical Medical College of Yangzhou University, Yangzhou, China.
Lei ZouDepartment of Infectious Diseases, Yancheng Second People's Hospital, Yancheng, China.
Dawen SangDepartment of Infectious Diseases, Yancheng Second People's Hospital, Yancheng, China.
Haiyan ZhaoDepartment of Infectious Diseases, The People's Hospital of Suqian, Suqian, China.
Xinying GuanDepartment of Neurology, The Affiliated Hospital of Kangda College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Xiaobing ChenDepartment of Emergency, The Affiliated Hospital of Kangda College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, China.
Chun ShanDepartment of Infectious Diseases, Zhongda Hospital Southeast University, Nanjing, China.
Juan XiaDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Yuxin ChenDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Xiaomin YanDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jie WeiDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Chuanwu ZhuDepartment of Infectious Diseases, The Affiliated Infectious Diseases Hospital of Soochow University, Suzhou, China.
Chao WuDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.ORCID 0000-0002-1657-010X
Nanjing Drum Tower Hospital · CNXuzhou Medical College · CNChangzhou Third People's Hospital · CNSoochow University · CNYancheng Second People's Hospital · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNThe First People’s Hospital of Lianyungang · CNNorthern Jiangsu People's Hospital · CNPeople's Hospital of Yangzhong · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized COVID-19 patients were retrospectively collected in 8 hospitals from 8 cities of Jiangsu province, China. Clinical findings of COVID-19 patients were described and risk factors for severe illness of COVID-19 were analyzed. By Feb 10, 2020, 202 hospitalized patients with COVID-19 were enrolled. The median age of patients was 44.0 years (interquartile range, 33.0-54.0). 55 (27.2%) patients had comorbidities. At the onset of illness, the common symptoms were fever (156 [77.2%]) and cough (120 [59.4%]). 66 (32.7%) patients had lymphopenia. 193 (95.5%) patients had abnormal radiological findings. 11 (5.4%) patients were admitted to the intensive care unit and none of the patients died. 23 (11.4%) patients had severe illness. Severe illness of COVID-19 was independently associated with body mass index (BMI) ≥ 28 kg/m2 (odds ratio [OR], 9.219; 95% confidence interval [CI], 2.731 to 31.126; P<0.001) and a known history of type 2 diabetes (OR, 4.326; 95% CI, 1.059 to 17.668; P = 0.041). In this case series in Jiangsu Province, COVID-19 patients had less severe symptoms and had better outcomes than the initial COVID-19 patients in Wuhan. The BMI ≥ 28 kg/m2 and a known history of type 2 diabetes were independent risk factors of severe illness in patients with COVID-19.

Indexed as

AdultBetacoronavirusBody Mass IndexChinaComorbidityCoronavirus InfectionsCoughCOVID-19Diabetes Mellitus, Type 2FemaleFeverHospitalizationHumansIntensive Care UnitsLymphopeniaMale

Identifiers

PMID32384078
PMCPMC7239492
OpenAlexW3013034900

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.