Trial reportJournal of medical Internet research2020
Usability, Acceptability, and Effectiveness of Web-Based Conversational Agents to Facilitate Problem Solving in Older Adults: Controlled Study.
Trial report in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Usability and User Experience Assessment of Health Care Conversational Agents Using Validated Subjective Instruments: Systematic Review and Comparative Analysis.JMIR human factors · 2026Pooled it
- Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Acceptability and Effectiveness of NHS-Recommended e-Therapies for Depression, Anxiety, and Stress: Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- Usability Comparison Among Healthy Participants of an Anthropomorphic Digital Human and a Text-Based Chatbot as a Responder to Questions on Mental Health: Randomized Controlled Trial.JMIR human factors · 2024Trial
- Mental Health Chatbot for Young Adults With Depressive Symptoms During the COVID-19 Pandemic: Single-Blind, Three-Arm Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- The Role of Multimodal Generative AI in Older Adults' Health Management: Systematic Scoping Review.JMIR AI · 2026Review
- Effectiveness of AI and rule-based conversational agents for depression, anxiety and stress: A meta-analysis.NPJ digital medicine · 2026Article
- Efficacy of AI-delivered cognitive behavioral therapy interventions for anxiety and depressive symptoms: a systematic review.NPJ digital medicine · 2026Article
- Current Landscape of Mental Health Conversational Agents From a Trauma-Informed Care Lens: Scoping Review.JMIR mental health · 2026Article
- User Experiences of a Chatbot for Supporting the Self-Management of Peripherally Inserted Central Catheter for Chemotherapy: Mixed Methods Study.JMIR cancer · 2026Article
- When a chatbot asks "How are you?": A cross-sectional study of AI call conversations and depressive symptom detection among older adults in rural South Korea.BMC geriatrics · 2026Article
- Charting the evolution of artificial intelligence mental health chatbots from rule-based systems to large language models: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Beyond the Scalpel: Assessing ChatGPT's potential as an auxiliary intelligent virtual assistant in oral surgery.Computational and structural biotechnology journal · 2024Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
- Evaluation framework for conversational agents with artificial intelligence in health interventions: a systematic scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Potential of AI-Driven Chatbots in Urology: Revolutionizing Patient Care Through Artificial Intelligence.Current urology reports · 2024Review
- Systematic review and meta-analysis of AI-based conversational agents for promoting mental health and well-being.NPJ digital medicine · 2023Review
- An Integrative Survey on Mental Health Conversational Agents to Bridge Computer Science and Medical Perspectives.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2023Article
- Factors Influencing the Acceptability, Acceptance, and Adoption of Conversational Agents in Health Care: Integrative Review.Journal of medical Internet research · 2023Review
- An Artificial Therapist (Manage Your Life Online) to Support the Mental Health of Youth: Co-Design and Case Series.JMIR human factors · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe usability and effectiveness of conversational agents (chatbots) that deliver psychological therapies is under-researched.
objectiveThis study aimed to compare the system usability, acceptability, and effectiveness in older adults of 2 Web-based conversational agents that differ in theoretical orientation and approach.
methodsIn a randomized study, 112 older adults were allocated to 1 of the following 2 fully automated interventions: Manage Your Life Online (MYLO; ie, a chatbot that mimics a therapist using a method of levels approach) and ELIZA (a chatbot that mimics a therapist using a humanistic counseling approach). The primary outcome was problem distress and resolution, with secondary outcome measures of system usability and clinical outcome.
resultsMYLO participants spent significantly longer interacting with the conversational agent. Posthoc tests indicated that MYLO participants had significantly lower problem distress at follow-up. There were no differences between MYLO and ELIZA in terms of problem resolution. MYLO was rated as significantly more helpful and likely to be used again. System usability of both the conversational agents was associated with helpfulness of the agents and the willingness of the participants to reuse. Adherence was high. A total of 12% (7/59) of the MYLO group did not carry out their conversation with the chatbot.
conclusionsControlled studies of chatbots need to be conducted in clinical populations across different age groups. The potential integration of chatbots into psychological care in routine services is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.