Evidence map›Paper›PMID 32384006›Full record

ArticleJournal of the American Heart Association2020

Hemodynamic Change of Coronary Atherosclerotic Plaque After Statin Treatment: A Serial Follow-Up Study by Computed Tomography-Derived Fractional Flow Reserve.

Mengmeng Yu, Xu Dai, Lihua Yu, Zhigang Lu, Chengxing Shen, Xiaofeng Tao, Jiayin Zhang

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengmeng YuInstitute of Diagnostic and Interventional Radiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Xu DaiInstitute of Diagnostic and Interventional Radiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Lihua YuInstitute of Diagnostic and Interventional Radiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Zhigang LuDepartment of Cardiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Chengxing ShenDepartment of Cardiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.
Xiaofeng TaoDepartment of Radiology Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Jiayin ZhangInstitute of Diagnostic and Interventional Radiology Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Whether statin treatment can improve hemodynamic status of coronary atherosclerotic plaque remains unknown. It is of clinical interest to explore the hemodynamic change of coronary lesions after statin treatment. Methods and Results Consecutive patients with intermediate pre-test probability of coronary artery disease were prospectively enrolled and underwent baseline coronary computed tomography angiography (CCTA) as well as follow-up CCTA. The primary end point was to determine the lesion-specific change of △computed tomography-derived fractional flow reserve (△CT-FFR, defined as the change of CT-FFR value across each lesion) after rosuvastatin treatment. The secondary end point was to compare the change of other plaque characteristics according to serial CCTA findings. 152 patients (mean age: 67.1±9.7 years, 100 men, mean follow-up duration of 13.9±2.5 months) were finally included. In non-calcified plaque subgroup, △CT-FFR was significantly lower at follow-up compared with baseline (0.051±0.010 versus 0.035±0.012,

Indexed as

Computed Tomography AngiographyCoronary AngiographyPlaque, AtheroscleroticAgedCoronary Artery DiseaseCoronary VesselsFemaleFractional Flow Reserve, MyocardialHemodynamicsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPredictive Value of TestsProspective StudiesRecovery of FunctionHydroxymethylglutaryl-CoA Reductase InhibitorsRosuvastatin Calciumcoronary artery diseasecoronary CT angiographyfractional flow reserveplaquestatin

Identifiers

PMID32384006
PMCPMC7660867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.