Evidence map›Paper›PMID 32383357›Full record

ArticleCancer medicine2020

PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells.

Silin Huang, Ying Zhu, Chunfei Wang, Xiaxi Li, Xiaobing Cui, Sufang Tu, Lijuan You, JingWen Fu, Zemin Chen, Wei Hu and 1 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. The Role of the p21-Activated Kinase Family in Tumor Immunity.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Article
  4. Rho family GTPase signaling through type II p21-activated kinases.Cellular and molecular life sciences : CMLS · 2022
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Silin HuangDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Ying ZhuDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Chunfei WangEndoscopy Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China.
Xiaxi LiDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Xiaobing CuiDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Sufang TuDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Lijuan YouDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
JingWen FuDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Zemin ChenDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Wei HuDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Wei GongDepartment of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.ORCID 0000-0003-2498-7615
Southern Medical University Shenzhen Hospital · CNChinese University of Hong Kong · HKSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third-most common cancer around the world, accounting for approximately 10% of cancer-related mortality. Deeper molecular understanding of colorectal carcinogenesis will provide evidences for identification of early diagnostic indicators and novel therapeutic strategies for CRC treatment. The p21

Indexed as

Animalscdc42 GTP-Binding ProteinCell MovementCell ProliferationColorectal NeoplasmsDisease ProgressionFemaleHumansIntegrin beta1Integrin beta3MiceMice, Inbred BALB CMice, NudeNeoplasm InvasivenessNeoplasm Proteinsp21-Activated Kinasescdc42 GTP-Binding ProteinCDC42 protein, humanIntegrin beta1Integrin beta3Neoplasm Proteinsp21-Activated KinasesPAK5 protein, humancolorectal cancerinvasionmigrationPAK5proliferation

Identifiers

PMID32383357
PMCPMC7333859
OpenAlexW3022673083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.