Evidence map›Paper›PMID 32383324›Full record

ArticleInternational wound journal2020

Cost of managing patients with venous leg ulcers.

Ceri J Phillips, Ioan Humphreys, Dan Thayer, Muhammad Elmessary, Huw Collins, Chris Roberts, Gurudutt Naik, Keith Harding

2 registry-linked trialsAbstract read
In one paragraph

Article in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05009940 naunknown statusnot on this mapstarted 2021, after this paper: background citation

A Clinical Investigation Evaluating the Efficacy of Gradusox™ Compression Hosiery at Enhancing Dermal Oxygen Levels in Healthy Participants Post-varicose Vein Surgery.

TypeinterventionalSponsorThe Whiteley ClinicRan2021 to 2021Enrolled32ConditionsEffect of Compression Hosiery on the Local Tissue Oxygenation and Compare This Effect Against That Achieved by Standard Compression HosieryArmsGraduated compression stockings
NCT05659394 nacompletednot on this mapstarted 2023, after this paper: background citation

Intermittent Pneumatic Compression of the Thigh for the Treatment of Lower Limb Wounds: a Randomised Control Trial

TypeinterventionalSponsorHuntleigh Healthcare LtdRan2023 to 2024Enrolled136ConditionsVenous Leg UlcerArmsStandard Wound Care Alone, Stand Wound Care plus IPC
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Transcriptomics in Venous Leg Ulcers (VLU): A Systematic Review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ceri J PhillipsCollege of Human and Health Sciences, Swansea University, Swansea, UK.
Ioan HumphreysCollege of Human and Health Sciences, Swansea University, Swansea, UK.ORCID https://orcid.org/0000-0001-7993-0179
Dan ThayerSAIL Databank: School of Medicine, Swansea University, Swansea, UK.
Muhammad ElmessarySAIL Databank: School of Medicine, Swansea University, Swansea, UK.
Huw CollinsSAIL Databank: School of Medicine, Swansea University, Swansea, UK.
Chris RobertsClinical Resolutions, Hessle, UK.
Gurudutt NaikWelsh Wound Innovation Centre, Cardiff University, Cardiff, UK.
Keith HardingWelsh Wound Innovation Centre, Cardiff University, Cardiff, UK.

Funding

Medical Ethics Pty, Melbourne Australia
6 · The paper itself

Abstract

The aim of this study was to estimate costs associated with the management of patients with venous leg ulcers (VLUs) from the perspective of the UK National Health Service (NHS). The analysis was undertaken through the Secure Anonymised Information Linkage Databank which brings together and anonymously links a wide range of person-based data from around 75% of general practitioner (GP) practices within Wales (population coverage ~2.5 million). The data covered an 11-year period from 2007 to 2017. All patients linked to the relevant codes were tracked through primary care settings, recording the number of GP practice visits (number of days with an event recorded), and wound treatment utilisation (eg, dressings, bandages, etc.) Resources were valued in monetary terms (£ sterling) and the costs were determined from national published sources of unit costs. This is the first attempt to estimate the costs of managing of VLUs using routine data sources. The direct costs to the Welsh NHS are considerable and represent 1.2% of the annual budget. Nurse visits are the main cost driver with annual estimates of £67.8 million. At a UK level, these costs amount to £1.98 billion. Dressings and compression bandages are also major cost drivers with annual Welsh estimates of £828 790. The direct cost of managing patients with VLUs is £7706 per patient per annum, which translates to an annual cost of over £2 billion, when extrapolated to the UK population. The primary cost driver is the number of district nurse visits. Initiatives to reduce healing times through improving accuracy of initial diagnosis, and improved evidence-based treatment pathways would result in major financial savings.

Indexed as

AgedAged, 80 and overChronic DiseaseCost-Benefit AnalysisFemaleHealth Care CostsHumansMaleMiddle AgedModels, EconomicState MedicineUnited KingdomVaricose UlcerWaleschronic woundseconomic burdenlinked routine dataVLUs

Identifiers

PMID32383324
PMCPMC7948848

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.