SynthesisInternational ophthalmology2020
Optic disc drusen: a systematic review : Up-to-date and future perspective.
Synthesis in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Dynamic pupillometry in patients with visible optic disc drusen: a cross-sectional study.BMC ophthalmology · 2026Article
- Artificial Intelligence in Neuro-Ophthalmology for Optic Disc Pathologies and Neurodegenerative Disease.Eye and brain · 2026Review
- Applications of Optical Coherence Tomography in Optic Nerve Head Diseases: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Imaging biomarkers in ophthalmology: hype, hope or game-changer?BMJ open ophthalmology · 2025Article
- Distinguishing Papilledema from Pseudopapilledema in Children.Advances in ophthalmology and optometry · 2024Article
- Article
- Optic nerve sheath diameter and axial length in patients with optic disc drusen: a cross-sectional study.International ophthalmology · 2023Article
- Morpho-Functional Assessment of Retinal Ganglion Cells and Visual Pathways in Patients with Optic Disc Drusen: Superficial Drusen Visible Height as a Marker of Impairment.Journal of clinical medicine · 2023Article
- Bilateral Progressive Optic Neuropathy in a Patient with Familial Amyloid Polyneuropathy: Amyloid Deposits in the Optic Nerve Head?Neuro-ophthalmology (Aeolus Press) · 2023Article
- Optic Nerve Drusen Evaluation: A Comparison between Ultrasound and OCT.Journal of clinical medicine · 2022Article
- Volumetric Measurement of Peripapillary Hyperreflective Ovoid Masslike Structures in Patients with Optic Disc Drusen.Ophthalmology science · 2022Article
- Visual field defects and retinal nerve fiber layer damage in buried optic disc drusen: a new insight.International journal of ophthalmology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptic disc drusen (ODD) are acellular deposits in the prelaminar optic nerve head. The most accredited theory is that they are secondary to abnormalities in axonal metabolism and degeneration, but the pathogenesis is not clear to date. CLINICAL MANIFESTATION: Although ODD are often considered a benign condition, the great majority of patients with ODD show visual field defects and are at higher risk for developing anterior ischemic optic neuropathy. ODD are classified as superficial or buried, with the latter being often misdiagnosed as papilledema with optic nerve head swelling, leading to an unnecessary investigation for causes of increased intracranial pressure.
aimThe recent technological improvements in OCT imaging which allowed an earlier and more certain diagnosis even of the smallest ODD, renovated the interest around this pathology. However, an updated systematic review is still missing. Therefore, the aim of this work is to provide a concise yet comprehensive overview of the current state of art, focusing on pathophysiology, clinical presentation, diagnostic methods, treatment modalities and potential future perspectives of this condition.
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