ArticleAnnals of intensive care2020
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Article in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Trial
- Beyond NIHSS and neuroimaging: an interpretable gradient boosting model for predicting in-hospital mortality in ICU patients with acute ischemic stroke.Scientific reports · 2026Article
- Extracranial organ dysfunction in non-traumatic subarachnoid hemorrhage: a retrospective single center cohort study.BMC anesthesiology · 2026Article
- Unraveling family resilience patterns in ICU first-episode stroke: a latent profile analysis.Frontiers in psychology · 2026Article
- Risk factors for prolonged mechanical ventilation in critically ill patients with ischemic stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Golden hour management in the patient with intraparenchymal cerebral hemorrhage: an Italian intersociety document.Journal of anesthesia, analgesia and critical care · 2025Review
- Outcome of Cerebral Venous Thrombosis Requiring Mechanical Ventilation.Journal of clinical medicine · 2025Article
- Airway management and functional outcomes in intubated patients with ischemic stroke.Scientific reports · 2025Article
- Serum creatinine-to-albumin ratio as a prognostic marker for short- and long-term mortality in critically ill stroke patients: a MIMIC-IV study.Frontiers in neurology · 2025Article
- Article
- Pulmonary consequences of experimentally induced stroke: differences between global and focal cerebral ischemia.Frontiers in physiology · 2024Article
- One-Year Survival of Ischemic Stroke Patients Requiring Mechanical Ventilation.Neurocritical care · 2023Article
- From Admission to Discharge: Predicting National Institutes of Health Stroke Scale Progression in Stroke Patients Using Biomarkers and Explainable Machine Learning.Journal of personalized medicine · 2023Article
- Prognostic value of initial routine laboratory blood tests in patients with aneurysmal subarachnoid hemorrhage requiring mechanical ventilation: a retrospective cohort study.Journal of thoracic disease · 2023Article
- [An interpretable machine learning-based prediction model for risk of death for patients with ischemic stroke in intensive care unit].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Preoperative systemic immune-inflammation index may predict prolonged mechanical ventilation in patients with spontaneous basal ganglia intracerebral hemorrhage undergoing surgical operation.Frontiers in neurology · 2023Article
- Outcomes of patients admitted to the ICU for acute stroke: a retrospective cohort.BMC anesthesiology · 2022Article
- Risk Factors and Prognosis in Patients With Anti-N-Methyl-D-Aspartate Receptor Encephalitis Requiring Prolonged Mechanical Ventilation.Frontiers in neurology · 2022Article
- Age-Specific and Sex-Specific Trends in Life-Sustaining Care After Acute Stroke.Journal of the American Heart Association · 2021Article
- Sleep Disorders in Stroke: An Update on Management.Aging and disease · 2021Review
Corrections and comments
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Authors and funding
19 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost prognostic studies in acute stroke patients requiring invasive mechanical ventilation are outdated and have limitations such as single-center retrospective designs. We aimed to study the association of ICU admission factors, including the reason for intubation, with 1-year survival of acute stroke patients requiring mechanical ventilation.
methodsWe conducted a secondary data use analysis of a prospective multicenter database (14 ICUs) between 1997 and 2016 on consecutive ICU stroke patients requiring mechanical ventilation at admission. We excluded patients with stroke of traumatic origin, subdural hematoma or cerebral venous thrombosis. The primary outcome was survival 1 year after ICU admission. Factors associated with the primary outcome were identified using a multivariable Cox model stratified on inclusion center.
resultsWe identified 419 patients (age 68 [58-76] years, males 60%) with a Glasgow coma score (GCS) of 4 [3-8] at admission. Stroke subtypes were acute ischemic stroke (AIS, 46%), intracranial hemorrhage (ICH, 42%) and subarachnoid hemorrhage (SAH, 12%). At 1 year, 96 (23%) patients were alive. Factors independently associated with decreased 1-year survival were ICH and SAH stroke subtypes, a lower GCS score at admission, a higher non-neurological SOFA score. Conversely, patients receiving acute-phase therapy had improved 1-year survival. Intubation for acute respiratory failure or coma was associated with comparable survival hazard ratios, whereas intubation for seizure was not associated with a worse prognosis than for elective procedure. Survival did not improve over the study period, but patients included in the most recent period had more comorbidities and presented higher severity scores at admission.
conclusionsIn acute stroke patients requiring mechanical ventilation, the reason for intubation and the opportunity to receive acute-phase stroke therapy were independently associated with 1-year survival. These variables could assist in the decision process regarding the initiation of mechanical ventilation in acute stroke patients.
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