Evidence map›Paper›PMID 32382789›Full record

ArticleEuropean journal of pediatrics2020

Ultrasound-guided supraclavicular cannulation of the brachiocephalic vein may reduce central line-associated bloodstream infection in preterm infants.

Ignacio Oulego-Erroz, Alba Fernández-García, Beatriz Álvarez-Juan, Sandra Terroba-Seara, Paula Alonso Quintela, Antonio Rodríguez-Núñez

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in European journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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  6. Insertion technologies for neonatal venous access: a scoping review.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ignacio Oulego-ErrozPediatric Intensive Care Unit, Complejo Asistencial Universitario de León, León, Spain. ignacio.oulego@gmail.com.ORCID http://orcid.org/0000-0002-9653-954X
Alba Fernández-GarcíaNeonatal Intensive Care Unit, Complejo Asistencial Universitario de León, León, Spain.
Beatriz Álvarez-JuanNeonatal Intensive Care Unit, Complejo Asistencial Universitario de León, León, Spain.
Sandra Terroba-SearaNeonatal Intensive Care Unit, Complejo Asistencial Universitario de León, León, Spain.
Paula Alonso QuintelaIBIOMED - Biomedicine Institute of León, University of León, León, Spain.
Antonio Rodríguez-NúñezPediatric Critical, Intermediate and Palliative Care Section, Hospital Clínico Universitario de Santiago, Research Institute of Santiago (IDIS), Santiago, Spain.
Complejo Asistencial Universitario de Palencia · ESInstituto de Investigación Sanitaria de Santiago · ESSpanish Society of Hematology and Hemotherapy · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to assess the risk of central line-associated bloodstream infection (CLABSI) of ultrasound (US)-guided cannulation of the brachiocephalic vein (BCV) compared to standard epicutaneous cava catheters (ECCs) in preterm infants. This was a retrospective cohort study in preterm infants with a birth weight of less than 1500 g. Each BCV catheter was matched 1:3 with ECCs according to sex, birth weight, and year of insertion. The main outcome was the CLABSI density rate per 1000 days. Secondary outcomes included CLABSI episodes, CLABSI episodes per infant, and CLABSI/death. A multivariate Cox regression analysis was performed to assess whether the type of catheter (ECC vs. BCV) was associated with CLABSI risk. Ninety-six catheters (21 BCVs and 75 ECCs) in 79 infants were included (993 catheter days). BCV catheters were associated with a reduced CLABSI density rate compared to ECCs (3.05/1000 days vs 21.1/1000 days; p < 0.001). ECCs were associated with increased CLABSI risk compared to BCV catheters in multivariate analysis (hazard ratio 36; (95% CI, 2.5-511); p = 0.008).Conclusion: US-guided supraclavicular cannulation of the BCV was associated with a reduced risk of CLABSI compared to ECCs. This finding deserves further multicenter research. What is Known: • An epicutaneous-cava catheter (ECC) is commonly used in preterm infants for routine care (eg. delivery of nutrition and antibiotics) but this device may not suffice in infants who need high-intensity care (multiple drugs, hemodynamic monitoring, fluid resuscitation etc.). • Ultrasound-guided brachiocephalic vein (BCV) catheterization has shown a high success rate and few immediate complications in neonates and small infants but it has never been compared to standard ECCs. What is New: • When the operator in properly trained, US guided cannulation of the BCV in preterm infants is feasible, safe and may reduce the risk of CLABSI compared to standard ECCs. • This fact may expand the use of BCV catheters in selected high-risk preterm infants who need a large bore venous access.

Indexed as

BacteremiaCatheterization, Central VenousCatheter-Related InfectionsCentral Venous CathetersBrachiocephalic VeinsHumansInfantInfant, NewbornInfant, PrematureRetrospective StudiesUltrasonography, InterventionalBrachiocephalic veinCentral line–associated bloodstream infectionEpicutaneous cava catheterPretermUltrasound

Identifiers

PMID32382789
PMCPMC7223997
OpenAlexW3022919950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.