Evidence map›Paper›PMID 32382736›Full record

Observational studyThe Journal of clinical endocrinology and metabolism2020

Racial-Ethnic Inequity in Young Adults With Type 1 Diabetes.

Shivani Agarwal, Lauren G Kanapka, Jennifer K Raymond, Ashby Walker, Andrea Gerard-Gonzalez, Davida Kruger, Maria J Redondo, Michael R Rickels, Viral N Shah, Ashley Butler and 5 more

2 registry-linked trialsAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in The Journal of clinical endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 124 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05734313 narecruitingnot on this mapstarted 2023, after this paper: background citation

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2023 to 2027Enrolled94ConditionsDiabetes, Type 1 DiabetesArmsUnified protocol for cognitive behavioral therapy (UP-CBT), Continuous Glucose Monitoring (CGM)
NCT06837181 recruitingnot on this mapstarted 2025, after this paper: background citation

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

TypeobservationalSponsorJaeb Center for Health ResearchRan2025 to 2028Enrolled200ConditionsCystic Fibrosis (CF), Cystic Fibrosis-related Diabetes, Diabetes, RetinopathyArmsobservational study
3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 1 synthesis or guideline pooled it.

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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shivani AgarwalFleischer Institute for Diabetes and Metabolism, New York-Regional Center for Diabetes Translational Research, Division of Endocrinology, Albert Einstein College of Medicine, Bronx, NY.
Lauren G KanapkaJaeb Center for Health Research, Tampa, FL.
Jennifer K RaymondChildren's Hospital Los Angeles, Los Angeles, CA.
Ashby WalkerUniversity of Florida, Gainesville, FL.
Andrea Gerard-GonzalezBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
Davida KrugerHenry Ford Medical Center, Detroit, MI.
Maria J RedondoBaylor College of Medicine, Texas Children's Hospital, Houston, TX.
Michael R RickelsInstitute for Diabetes, Obesity & Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Viral N ShahBarbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
Ashley ButlerBaylor College of Medicine, Texas Children's Hospital, Houston, TX.
Jeffrey GonzalezFleischer Institute for Diabetes and Metabolism, New York-Regional Center for Diabetes Translational Research, Division of Endocrinology, Albert Einstein College of Medicine, Bronx, NY.
Alandra S VerdejoJaeb Center for Health Research, Tampa, FL.
Robin L GalJaeb Center for Health Research, Tampa, FL.
Steven WilliChildren's Hospital of Philadelphia, Philadelphia, PA.
Judith A LongInstitute for Diabetes, Obesity & Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

Funding

Stable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Identifying and Reducing Disparities in Outcomes Among Economically Vulnerable and Minority Young Adults with Type 1 DiabetesK23DK115896 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AGARWAL, SHIVANI · 2018 to 2022
$988k
NIDDK NIH HHS K23 DK115896NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P60 DK020541
6 · The paper itself

Abstract

contextMinority young adults (YA) currently represent the largest growing population with type 1 diabetes (T1D) and experience very poor outcomes. Modifiable drivers of disparities need to be identified, but are not well-studied.

objectiveTo describe racial-ethnic disparities among YA with T1D and identify drivers of glycemic disparity other than socioeconomic status (SES).

designCross-sectional multicenter collection of patient and chart-reported variables, including SES, social determinants of health, and diabetes-specific factors, with comparison between non-Hispanic White, non-Hispanic Black, and Hispanic YA and multilevel modeling to identify variables that account for glycemic disparity apart from SES.

settingSix diabetes centers across the United States.

participantsA total of 300 YA with T1D (18-28 years: 33% non-Hispanic White, 32% non-Hispanic Black, and 34% Hispanic). MAIN OUTCOME: Racial-ethnic disparity in HbA1c levels.

resultsNon-Hispanic Black and Hispanic YA had lower SES, higher HbA1c levels, and much lower diabetes technology use than non-Hispanic White YA (P < 0.001). Non-Hispanic Black YA differed from Hispanic, reporting higher diabetes distress and lower self-management (P < 0.001). After accounting for SES, differences in HbA1c levels disappeared between non-Hispanic White and Hispanic YA, whereas they remained for non-Hispanic Black YA (+ 2.26% [24 mmol/mol], P < 0.001). Diabetes technology use, diabetes distress, and disease self-management accounted for a significant portion of the remaining non-Hispanic Black-White glycemic disparity.

conclusionThis study demonstrated large racial-ethnic inequity in YA with T1D, especially among non-Hispanic Black participants. Our findings reveal key opportunities for clinicians to potentially mitigate glycemic disparity in minority YA by promoting diabetes technology use, connecting with social programs, and tailoring support for disease self-management and diabetes distress to account for social contextual factors.

Indexed as

Health Status DisparitiesSocial ClassBlood Glucose Self-MonitoringCross-Sectional StudiesDiabetes Mellitus, Type 1EthnicityFemaleGlycated HemoglobinHumansMaleMinority GroupsPatient ComplianceRacial GroupsSelf-ManagementSocial Determinants of HealthUnited StatesGlycated Hemoglobinhemoglobin A1c protein, humanhealthcare disparitiesinequitysocial determinants of healthtype 1 diabetesyoung adults

Identifiers

PMID32382736
PMCPMC7457963

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.