Evidence map›Paper›PMID 32382572›Full record

Trial reportBioMed research international2020

Determinants of Risk Factors for Renal Impairment among HIV-Infected Patients Treated with Tenofovir Disoproxil Fumarate-Based Antiretroviral Regimen in Southern Vietnam.

Cuong Q Hoang, Hai D Nguyen, Huy Q Vu, Khai T Nguyen, Linh T Hoang, Hong Ly, Thang D Tat, Lan T Phan

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cuong Q HoangHo Chi Minh City Pasteur Institute, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0003-1934-7138
Hai D NguyenPlanning Department, Ho Chi Minh City Pasteur Institute, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0001-8419-7784
Huy Q VuMedical Testing Centers, HCMC Medical University, Ho Chi Minh, Vietnam.ORCID https://orcid.org/0000-0003-3509-1814
Khai T NguyenSoc Trang HIV/AIDS Prevention Centers, Soc Trang, Vietnam.
Linh T HoangMedical Testing and Calibration Centers, Ho Chi Minh City Pasteur Institute, Ho Chi Minh, Vietnam.
Hong LySoc Trang HIV/AIDS Prevention Centers, Soc Trang, Vietnam.
Thang D TatSoc Trang HIV/AIDS Prevention Centers, Soc Trang, Vietnam.
Lan T PhanHo Chi Minh City Pasteur Institute, Ho Chi Minh, Vietnam.
Institut Pasteur in Ho Chi Minh City · VNUniversity Medical Center HCMC · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe situation of renal impairment among HIV-infected patients treated with TDF-based antiretroviral (ARV) regimen greater than 3 years is little known when TDF use has been promptly increasing in Vietnam.

methodsWe analyse demographic and clinical data from a cross-sectional survey of 400 HIV-infected patients aged ≥18 years, who were treatment-naive or switched TDF regimen within over 3 years between November 2018 and March 2019. Serological tests for serum creatinine, ALT, and AST were performed. Renal impairment was defined as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m

resultsAt the baseline, 7.8% of respondents had estimated glomerular filtration rate (eGFR) of 30-59 mL/min/1.73 m

conclusionOur findings underscore the need for longitudinal studies to assess the influence of TDF on maintaining the low prevalence of renal impairment among HIV-infected patients in Vietnam.

Indexed as

Anti-Retroviral AgentsHIV-1HIV InfectionsKidney DiseasesTenofovirAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsVietnamAnti-Retroviral AgentsTenofovir

Identifiers

PMID32382572
PMCPMC7199550
OpenAlexW3000326213

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.