Evidence map›Paper›PMID 32382560›Full record

SynthesisBioMed research international2020

Extracorporeal Membrane Oxygenation in Cardiogenic Shock due to Acute Myocardial Infarction: A Systematic Review.

Marius Andrei Zavalichi, Ionut Nistor, Alina-Elena Nedelcu, Simona Daniela Zavalichi, Cătălina Marina Arsenescu Georgescu, Cristian Stătescu, Adrian Covic

Abstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Admission blood glucose level and outcome in patients requiring venoarterial extracorporeal membrane oxygenation.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marius Andrei ZavalichiCardiovascular Diseases Institute "Prof. Dr. George I.M. Georgescu", "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0002-5987-5173
Ionut Nistor"C. I. Parhon" University Hospital, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0002-1641-8992
Alina-Elena NedelcuRehabilitation Clinical Hospital, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0001-5516-0579
Simona Daniela ZavalichiRehabilitation Clinical Hospital, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0002-7005-3189
Cătălina Marina Arsenescu GeorgescuCardiovascular Diseases Institute "Prof. Dr. George I.M. Georgescu", "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0001-5142-7598
Cristian StătescuCardiovascular Diseases Institute "Prof. Dr. George I.M. Georgescu", "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0001-6439-4561
Adrian Covic"C. I. Parhon" University Hospital, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.ORCID https://orcid.org/0000-0002-9985-2486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiogenic shock is associated with high mortality, despite new strategies for reperfusion therapy. Short-term circulatory support devices may provide adequate support for appropriate myocardial and organ perfusion.

objectivesThis review is aimed at evaluating the impact on survival when using venoarterial extracorporeal membrane oxygenation (V-A ECMO) in patients with cardiogenic shock due to acute myocardial infarction (AMI).

methodsWe performed a systematic review that included studies using V-A ECMO in patients with cardiogenic shock. Time on ECMO, side effects, and the number of deceased patients, transplanted or upgraded to durable assist devices were analysed. Literature search was done using PubMed/MEDLINE (inception (1969) to January 10, 2019), ProQuest (inception (January 14, 1988) to January 10, 2019), and clinicaltrials.gov (inception (September 12, 2005) to January 10, 2019), by 2 authors. This protocol is registered with PROSPERO (no. CRD42019123982).

resultsWe included 9 studies with a total of 1,998 adult patients receiving V-A ECMO for AMI-induced cardiogenic shock. Survival rate varied from 30.0% to 79.2% at discharge and from 23.2% to 36.1% at 12 months. Time on ECMO varied between 1.96 and 6.0 days. Reported serious adverse events were gastrointestinal bleeding (3.6%) and peripheral complications (8.5%).

conclusionThe use of V-A ECMO among patients with AMI-induced cardiogenic shock may provide survival benefits. However, V-A ECMO treatment effects are inconclusive because of limitations in cohort design and reporting.

Indexed as

Extracorporeal Membrane OxygenationDisease-Free SurvivalHumansMyocardial InfarctionShock, CardiogenicSurvival Rate

Identifiers

PMID32382560
PMCPMC7193268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.