Evidence map›Paper›PMID 32382553›Full record

Trial reportBioMed research international2020

Interaction of miR-181b and

Yong-Ling He, Jun Yang, Zhi-Neng Zeng, Xiang Shi

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Expert opinion on therapeutic targets · 2024
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yong-Ling HeDepartment of Laboratory Medicine, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.ORCID https://orcid.org/0000-0002-4786-7176
Jun YangDepartment of Laboratory Medicine, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.
Zhi-Neng ZengDepartment of Laboratory Medicine, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.
Xiang ShiDepartment of Laboratory Medicine, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China.
Guilin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA previous work has discovered that chromosome 1q32 locus linked to the risk of systemic lupus erythematosus (SLE) and miR-181b located on the susceptibility site with downregulation inversely correlating to its target molecular interferon alpha 1 (

methodsThe miR-181b rs322931,

resultsThe rs322931 CT, CT/TT, and T allele exerted an increased trend of SLE risk (CT vs. CC: adjusted OR = 1.71, 95% CI 1.16-2.50,

conclusionsThese findings indicate that the miR-181b rs322931 may be singly and jointly responsible for the etiology of SLE by altering miR-181b expression.

Indexed as

Genetic Association StudiesInterferon-alphaLupus Erythematosus, SystemicMicroRNAsModels, GeneticMultifactorial InheritancePolymorphism, GeneticAdolescentAdultFemaleHumansMaleMiddle AgedIFNA1 protein, humanInterferon-alphaMicroRNAsMIrn181 microRNA, human

Identifiers

PMID32382553
PMCPMC7196983
OpenAlexW3020651211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.