Evidence map›Paper›PMID 32382533›Full record

ArticleBioMed research international2020

The Role of a Selective P2Y

Xiao Du, Shilan Zhang, Qunyan Xiang, Jingyuan Chen, Feng Tian, Jin Xu, Xin Li, Yuansheng Tan, Ling Liu

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Erratum to "The Role of a Selective P2YBioMed research international · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Xiao DuDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Shilan ZhangDepartment of Gastroenterology, Central South University, Changsha, Hunan 410011, China.
Qunyan XiangDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Jingyuan ChenDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Feng TianDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Jin XuDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Xin LiDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.
Yuansheng TanMinistry of Education, Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410011, China.
Ling LiuDepartment of Cardiovascular Medicine, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0001-6979-701X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe P2Y

methodsMale apoE

resultsTreatment with MRS2578 made no significant difference in AAA formation, and maximal aortic diameter yet caused higher AAA rupture-induced mortality from 7% (Ang II) to 21.4% (Ang II+MRS-16 mg) or 42.9% (Ang II+MRS-32 mg), respectively (

conclusionsThe present study demonstrated that administration of MRS2578 exacerbated the progression and rupture of experimental AAA through promoting proinflammatory response and MMP expression and activity, which indicated a crucial role of the P2Y

Indexed as

Angiotensin IIAortic Aneurysm, AbdominalIsothiocyanatesPurinergic AntagonistsAnimalsDisease Models, AnimalMiceMice, Knockout, ApoEReceptors, Purinergic P2ThioureaAngiotensin IIIsothiocyanatesN,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thioureaPurinergic Antagonistspurinoceptor P2Y6Receptors, Purinergic P2Thiourea

Identifiers

PMID32382533
PMCPMC7184271

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.