Evidence map›Paper›PMID 32382287›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Ferulic Acid Protects against Porcine Parvovirus Infection-Induced Apoptosis by Suppressing the Nuclear Factor-

Xia Ma, Zhenhuan Guo, Zhiqiang Zhang, Xianghui Li, Yonglu Liu, Li Zhao, Xuefei Wang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xia MaCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-9669-1760
Zhenhuan GuoCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Zhiqiang ZhangDepartment of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Xianghui LiCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Yonglu LiuCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Li ZhaoCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Xuefei WangCollege of Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Henan University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine parvovirus (PPV) infection-induced apoptosis was recently identified as an important pathological factor in PPV-induced placental tissue damage, resulting in reproduction failure. In the present study, we demonstrate the possible involvement of toll-like receptor (TLR) 4 and nuclear factor (NF)-

resultsFA inhibited PPV infection-induced inflammasome activation as shown by decreases in the expression of NF-

conclusionsFA downregulated NS1 and TLR4 signaling, prevented the overproduction of reactive oxygen species, and suppressed the NF-

Identifiers

PMID32382287
PMCPMC7199543
OpenAlexW3017853948

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.