ArticleGastroenterology research and practice2020
Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice.
Article in Gastroenterology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Association between oxidative balance score and gallstone risk and gallbladder surgery: A cross-sectional study.The Journal of international medical research · 2026Article
- Association between weekly sleep duration and gallstones in a US-based adult sample: A cross-sectional study.Medicine · 2025Article
- Association of dietary quality indicators with gallstones in the US: NHANES 2017-2020.BMC public health · 2025Article
- Polydatin prevents cholesterol gallstone formation by regulating cholesterol metabolism via PPAR-γ signaling.Open life sciences · 2025Article
- Methylation changes of liver DNA during the formation of gallstones.Epigenomics · 2024Article
- Osteopontin (SPP1) expression on gallstone formation in rabbits fed with a lithogenic diet.Journal of advanced veterinary and animal research · 2023Article
- Obesity and Gallstones.Visceral medicine · 2021Review
- Protective effect of Glechoma hederacea extract against gallstone formation in rodent models.BMC complementary medicine and therapies · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was aimed at investigating the effect of baicalin on experimental cholesterol gallstones in mice. The mouse gallstone model was induced by feeding with a lithogenic diet, and cholesterol stones were found in the gallbladder. The lithogenic diet caused elevation of triglycerides, cholesterol, and low-density lipoprotein concentrations and descent of high-density lipoprotein concentration in serum. Hyperplasia and inflammatory infiltration were observed in the gallbladder wall of lithogenic diet-fed mice. We also found the increase of cholesterol content and the decrease of bile acid in bile. Real-time PCR and western blot results demonstrated that the expression levels of two enzymes (cholesterol 7
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.