ReviewAnnals of gastroenterology
Pulmonary manifestations of chronic liver disease: a comprehensive review.
Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Pulmonary Complications in Cirrhosis: Current Concepts and Clinical Perspectives.Biomedicines · 2026Review
- Clinical aspects encountered in patients with portopulmonary hypertension.Medicine and pharmacy reports · 2025Review
- Prevalence and Predictors of Pulmonary Hypertension in Children with Portal Hypertension: A Single Center Study.Pediatric gastroenterology, hepatology & nutrition · 2025Article
- Beyond the lungs: extending the field-of-view in chest CT with latent diffusion models.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Alcoholic cardiomyopathy: an update.European heart journal · 2024Review
- Hemodynamic and Clinical Response to Liver Transplantation in Children and Young Adults POPH Patients.Pediatric cardiology · 2024Article
- The regional disparities in liver disease comorbidity among elderly Chinese based on a health ecological model: the China Health and Retirement Longitudinal Study.BMC public health · 2024Article
- Respiratory problems associated with liver disease in children.Breathe (Sheffield, England) · 2024Review
- Gut Microbiota and Biomarkers of Endothelial Dysfunction in Cirrhosis.International journal of molecular sciences · 2024Article
- [Pulmonary Complications in Patients with Liver Cirrhosis].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Imaging in hepatopulmonary syndrome-case report. A multicenter approach during the coronavirus pandemic.Journal of radiology case reports · 2023Article
- Portopulmonary Hypertension: An Updated Review.Transplantation direct · 2023Review
- Portopulmonary hypertension: a patient with shortness of breath.BMJ case reports · 2022Article
- Cardiac autonomic modulation in children with severe liver disease, before and after liver transplantation.Translational pediatrics · 2022Article
- Unmasking Hypoxia in Cirrhosis Patients: Six-Minute Walk Test as a Screening Tool for Hepatopulmonary Syndrome.Advanced biomedical research · 2022Article
- Assessment of biventricular function in patients with hepatopulmonary syndrome.The international journal of cardiovascular imaging · 2021Article
- Cardiac and renal effects of liver cirrhosis in a growing animal model.Acta cirurgica brasileira · 2021Article
- Article
- Pulmonary Dysfunction in Patients with Cirrhosis of the Liver: A Study of Pulmonary Function Tests and Arterial Blood Gases.International journal of applied & basic medical researchArticle
- LTSI Consensus Guidelines: Preoperative Pulmonary Evaluation in Adult Liver Transplant Recipients.Journal of clinical and experimental hepatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatopulmonary syndrome (HPS) and porto-pulmonary hypertension (PoPH) represent relatively common pulmonary vascular complications of advanced liver disease. Despite distinct differences in their pathogenetic background, both clinical states are characterized by impaired arterial oxygenation and limited functional status, and are associated with increased pre-transplantation mortality. Accumulation of ascitic fluid in the pleural cavity, known as hepatic hydrothorax (HH), is another frequent manifestation of decompensated cirrhosis, which may cause severe respiratory dysfunction, depending on the volume of the effusion, the rapidity of its development and its resistance to therapeutic measures. Orthotopic liver transplantation constitutes the only effective treatment able to resolve the pulmonary complications of liver disease. A prioritization policy for liver transplantation has evolved over the past years regarding advanced stages of HPS, yielding favorable outcomes regarding post-transplantation survival and HPS resolution. In contrast, severe PoPH is associated with poor post-transplantation survival. Hence, liver transplantation is recommended only for patients with PoPH and an acceptable reduction in pulmonary pressure values, after receiving PoPH-targeted vasodilating therapy. This review focuses on basic pathogenetic and diagnostic principles and discusses the current therapeutic approaches regarding HPS, PoPH, and HH.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.