ArticleNature communications2020
Photobiocatalytic synthesis of chiral secondary fatty alcohols from renewable unsaturated fatty acids.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 106 citations in OpenAlex.
- Nature-Inspired Enzymatic Cascades: Emerging Strategies for Sustainable Chemistry.Molecules (Basel, Switzerland) · 2026Review
- Research progress on intestinal probiotics-mediated protection of the intestinal mucosal barrier in ulcerative colitis.Frontiers in immunology · 2026Review
- Integrating incompatible tandem photobiocatalysis in artificial cells enables metabolic modulation of natural cells.Science advances · 2025Article
- Transitioning enzyme catalysis towards photocatalysis.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Review
- Cavity-Based Discovery of New Fatty Acid Photodecarboxylases.Chembiochem : a European journal of chemical biology · 2024Article
- Decarboxylation in Natural Products Biosynthesis.JACS Au · 2024Review
- Article
- Photobiocatalytic Strategies for Organic Synthesis.Chemical reviews · 2023Review
- Autocatalytic effect boosts the production of medium-chain hydrocarbons by fatty acid photodecarboxylase.Science advances · 2023Article
- Immobilization and Application of Fatty Acid Photodecarboxylase in Deep Eutectic Solvents.Chembiochem : a European journal of chemical biology · 2022Article
- Ultrafast Dynamics of Fatty Acid Photodecarboxylase in Anionic Semiquinone State.The journal of physical chemistry letters · 2022Article
- Strategies for Transferring Photobiocatalysis to Continuous Flow Exemplified by Photodecarboxylation of Fatty Acids.ACS catalysis · 2022Article
- Triplet-triplet annihilation-based photon-upconversion to broaden the wavelength spectrum for photobiocatalysis.Scientific reports · 2022Article
- Simple Plug-In Synthetic Step for the Synthesis of (-)-Camphor from Renewable Starting Materials.Chembiochem : a European journal of chemical biology · 2021Article
- Novel oleate hydratases and potential biotechnological applications.Applied microbiology and biotechnology · 2021Review
- Stabilisation of the Fatty Acid Decarboxylase from Chlorella variabilis by Caprylic Acid.Chembiochem : a European journal of chemical biology · 2021Article
- A Reconstructed Common Ancestor of the Fatty Acid Photo-decarboxylase Clade Shows Photo-decarboxylation Activity and Increased Thermostability.Chembiochem : a European journal of chemical biology · 2021Article
- Light-Driven Enzymatic Decarboxylation of Dicarboxylic Acids.ChemistryOpen · 2021Article
- Photo-biocatalytic Cascades: Combining Chemical and Enzymatic Transformations Fueled by Light.Chembiochem : a European journal of chemical biology · 2021Review
- Intensification of Photobiocatalytic Decarboxylation of Fatty Acids for the Production of Biodiesel.ChemSusChem · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
En route to a bio-based chemical industry, the conversion of fatty acids into building blocks is of particular interest. Enzymatic routes, occurring under mild conditions and excelling by intrinsic selectivity, are particularly attractive. Here we report photoenzymatic cascade reactions to transform unsaturated fatty acids into enantiomerically pure secondary fatty alcohols. In a first step the C=C-double bond is stereoselectively hydrated using oleate hydratases from Lactobacillus reuteri or Stenotrophomonas maltophilia. Also, dihydroxylation mediated by the 5,8-diol synthase from Aspergillus nidulans is demonstrated. The second step comprises decarboxylation of the intermediate hydroxy acids by the photoactivated decarboxylase from Chlorella variabilis NC64A. A broad range of (poly)unsaturated fatty acids can be transformed into enantiomerically pure fatty alcohols in a simple one-pot approach.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.