ArticleNature communications2020
Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease.
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Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
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Who cites it
18 citing papers in PubMed, 24 citations in OpenAlex.
- Cancer treatment alters mutant selection in normal esophagus.Nature genetics · 2026Article
- Article
- CKMT1B regulates the proliferation, migration, invasion, and apoptosis of colorectal cancer cells through the AKT/mTOR/STAT3 pathway.Molecular genetics and genomics : MGG · 2025Article
- Somatic mutations associate with clonal expansion of CD8Science advances · 2024Article
- Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia.Cell reports. Medicine · 2024Article
- Cytotoxic CD4Med (New York, N.Y.) · 2023Article
- Immunologic Characterization and T cell Receptor Repertoires of Expanded Tumor-infiltrating Lymphocytes in Patients with Renal Cell Carcinoma.Cancer research communications · 2023Article
- Clonal hematopoiesis, somatic mosaicism, and age-associated disease.Physiological reviews · 2023Review
- Hsp90 Activity Is Necessary for the Maturation of Rabies Virus Polymerase.International journal of molecular sciences · 2022Article
- Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8Nature communications · 2022Article
- Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia.Blood cancer journal · 2022Article
- SomaticHaematologica · 2022Article
- STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation.Leukemia · 2021Article
- Review
- The Role of mTOR Signaling as a Therapeutic Target in Cancer.International journal of molecular sciences · 2021Review
- Natural Barcodes for Longitudinal Single Cell Tracking of Leukemic and Immune Cell Dynamics.Frontiers in immunology · 2021Review
- Kinase Inhibition as Treatment for Acute and Chronic Graft-Frontiers in immunology · 2021Review
- Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature.Frontiers in immunology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 2 countries.
Daehong Kim *Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0002-1253-8946
Giljun Park *Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0001-6044-6838
Jani HuuhtanenHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0003-2750-4033
Sofie LundgrenHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.
Rajiv K KhajuriaHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.
Ana M HurtadoHematology and Medical Oncology Department, Hospital Morales Meseguer. Centro Regional de Hemodonación, Universidad de Murcia, IMIB, 30008, Murcia, Spain.ORCID http://orcid.org/0000-0002-3235-3690
Cecilia Muñoz-CallejaDepartment of Immunology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, 28006, Madrid, Spain.
Laura CardeñosoDepartment of Microbiology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, 28006, Madrid, Spain.
Valle Gómez-García de SoriaDepartment of Hematology, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, 28006, Madrid, Spain.
Tzu Hua Chen-LiangHematology and Medical Oncology Department, Hospital Morales Meseguer. Centro Regional de Hemodonación, Universidad de Murcia, IMIB, 30008, Murcia, Spain.ORCID http://orcid.org/0000-0001-5969-8640
Samuli EldforsInstitute of Molecular Medicine Finland (FIMM), University of Helsinki, 00014, Helsinki, Finland.ORCID http://orcid.org/0000-0001-5056-4750
Pekka EllonenInstitute of Molecular Medicine Finland (FIMM), University of Helsinki, 00014, Helsinki, Finland.
Sari HannulaInstitute of Molecular Medicine Finland (FIMM), University of Helsinki, 00014, Helsinki, Finland.
Matti KankainenHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.
Oscar BruckHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0002-7842-9419
Anna KreutzmanHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.
Urpu SalmenniemiStem Cell transplantation unit, Turku University Hospital, 20521, Turku, Finland.
Tapio LönnbergTurku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland.
Andrés JerezHematology and Medical Oncology Department, Hospital Morales Meseguer. Centro Regional de Hemodonación, Universidad de Murcia, IMIB, 30008, Murcia, Spain.
Maija Itälä-RemesStem Cell transplantation unit, Turku University Hospital, 20521, Turku, Finland.
Mikko MyllymäkiHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.ORCID http://orcid.org/0000-0002-8194-7356
Mikko A I KeränenHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland.
Satu MustjokiHematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, 00290, Helsinki, Finland. satu.mustjoki@helsinki.fi.ORCID http://orcid.org/0000-0002-0816-8241
University of Helsinki · FICentro Regional de Hemodonación · ESHospital Universitario de La Princesa · ESTurku University Hospital · FIÅbo Akademi University · FIHelsinki University Hospital · FI
Funding
No grant is acknowledged in the PubMed record.
Abstract
Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient with chronic GvHD (cGvHD) carrying persistent CD4
Indexed as
Blotting, WesternCell ProliferationGraft vs Host DiseaseHEK293 CellsHumansImmunity, CellularImmunoprecipitationMutationProtein BindingT-LymphocytesTOR Serine-Threonine KinasesMTOR protein, humanTOR Serine-Threonine Kinases
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.