ArticleHaematologica2021
The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia.
Open access · goldAbstract readLetter
In one paragraph
Article in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 56 citations in OpenAlex.
- Immunophenotyping of Acute Myeloid Leukemia.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Immunophenotypic, Cytogenetic, and Molecular Characterization of NUP98-Rearranged Pediatric Myeloid Neoplasms.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2026Article
- [Prognostic analysis of NUP98 rearrangement in patients with pediatric acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2026Article
- Preferential formation of NUP98-KDM5A condensates at specific H3K4me3-rich loci drives leukemogenic gene expression.bioRxiv : the preprint server for biology · 2026Article
- KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia.Cancer discovery · 2025Article
- Clinically associated genomic landscape of pediatric non-Down Syndrome acute megakaryoblastic leukemia in Chinese patients.Leukemia · 2025Article
- HTS Identifies NUP98-KDM5A-PHD3 Domain Ligands with Novel Scaffolds.ACS medicinal chemistry letters · 2025Article
- Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12.Nature communications · 2025Article
- Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization.Nucleic acids research · 2025Article
- Review
- Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia.Molecular cancer · 2024Article
- Targeted gene sequencing and transcriptome sequencing reveal characteristics of NUP98 rearrangement in pediatric acute myeloid leukemia.European journal of medical research · 2024Article
- NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunities.HemaSphere · 2024Review
- Acute myeloid leukemia with rare recurring translocations-an overview of the entities included in the international consensus classification.Annals of hematology · 2024Review
- Prognostic importance of NUP98-rearrangements in acute myeloid leukemia: A systematic review and meta-analysis.Caspian journal of internal medicine · 2024Review
- Therapeutic targeting in pediatric acute myeloid leukemia with aberrant HOX/MEIS1 expression.European journal of medical genetics · 2023Review
- Prospective evaluation of genome sequencing to compare conventional cytogenetics in acute myeloid leukemia.Blood cancer journal · 2023Article
- Article
- The MLL-Menin Interaction is a Therapeutic Vulnerability inHemaSphere · 2023Article
- Comprehensive molecular and clinical characterization ofHaematologica · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 5 countries.
Sanne NoortPediatric Oncology/Hematology, Erasmus MC-Sophia Children Hospital Rotterdam, The Netherlands.
Priscilla WanderPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Todd A AlonzoChildren's Oncology Group, Monrovia, California, USA.
Jenny SmithFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Rhonda E RiesFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Robert B GerbingChildren's Oncology Group, Monrovia, California, USA.
M Emmy M DolmanPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Franco LocatelliIRCCS Ospedale Bambino Gesú, Sapienza, University of Rome, Rome, Italy.
Dirk ReinhardtAML-BFM Study Group, Pediatric Hematology and Oncology, Essen, Germany.
Andre BaruchelUniversity Hospital Robert Debré and Paris Diderot University, Paris, France.
Jan StaryCPH, University Hospital Motol and Charles University, Prague, Czech Republic.
Jan J MolenaarPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Ronald W StamPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Marry M van den Heuvel-EibrinkPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Michel C ZwaanPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Soheil MeshinchiDepartment of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, USA.
Princess Máxima Center · NLChildren's Oncology Group · USFred Hutch Cancer Center · USBambino Gesù Children's Hospital · ITCharles University · CZErasmus MC - Sophia Children’s Hospital · NLSeattle Children's Hospital · USUniversité Paris Cité · FR
Funding
NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6MCOG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8MNCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
Abstract
PubMed holds no abstract for this paper.
Indexed as
Leukemia, Myeloid, AcuteNuclear Pore Complex ProteinsChildHomeodomain ProteinsHumansOncogene Proteins, FusionRetinoblastoma-Binding Protein 2Translocation, GeneticHomeodomain ProteinsKDM5A protein, humannuclear pore complex protein 98Nuclear Pore Complex ProteinsNup98 protein, humanOncogene Proteins, FusionRetinoblastoma-Binding Protein 2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.