Evidence map›Paper›PMID 32381556›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2020

Effect of a Digital Health Intervention on Decreasing Barriers and Increasing Facilitators for Colorectal Cancer Screening in Vulnerable Patients.

Nancy M Denizard-Thompson, David P Miller, Anna C Snavely, John G Spangler, L Doug Case, Kathryn E Weaver

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Pooled it
  4. Article
  5. The effectiveness of mobile health intervention in colorectal cancer screening in Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nancy M Denizard-ThompsonInternal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina. ndenizar@wakehealth.edu.
David P MillerInternal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0001-7879-4427
Anna C SnavelySocial Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina.
John G SpanglerDepartment of Family and Community Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina.
L Doug CaseSocial Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Kathryn E WeaverSocial Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0001-9006-4064
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
A Primary Care Multilevel mHealth Colorectal Cancer Screening (mCRC) InterventionR01CA178941 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2013 to 2016
$1.4M
NCATS NIH HHS UL1 TR001420NCI NIH HHS P30 CA012197NCI NIH HHS R01 CA178941
6 · The paper itself

Abstract

backgroundColorectal cancer is the second leading cause of cancer-related death in the United States, in part, because one third of Americans fail to get screened. In a prior randomized controlled trial, we found that an iPad patient decision aid called Mobile Patient Technology for Health-CRC (mPATH-CRC) doubled the proportion of patients who completed colorectal cancer screening.

methodsAll data for the current analysis were collected as part of a randomized controlled trial to determine the impact of mPATH-CRC on receipt of colorectal cancer screening within 24 weeks. Participants were enrolled from six community-based primary care practices between June 2014 and May 2016 and randomized to either usual care or mPATH-CRC. Six potential mediators of the intervention effect on screening were considered. The Iacobucci method was used to assess the significance of the mediation.

resultsA total of 408 patients had complete data for all potential mediators. Overall, the potential mediators accounted for approximately three fourths (76.3%) of the effect of the program on screening completion. Perceived benefits, self-efficacy, ability to state a screening decision, and patient-provider discussion were statistically significant mediators. Patient-provider discussion accounted for the largest proportion of the effect of mPATH-CRC (70.7%).

conclusionsmPATH-CRC increased completion of colorectal cancer screening by affecting patient-level and system-level mediators. However, the most powerful mediator was the occurrence of a patient-provider discussion about screening. Digital interventions like mPATH-CRC are an important adjunct to the patient-provider encounter. IMPACT: Understanding the factors that mediated mPATH-CRC's success is paramount to developing other effective interventions.

Indexed as

AgedColorectal NeoplasmsDecision Support TechniquesFemaleHumansMaleMiddle AgedUnited StatesVulnerable Populations

Identifiers

PMID32381556
PMCPMC7416430
OpenAlexW3023553524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.