Evidence map›Paper›PMID 32381535›Full record

ArticleBMJ open2020

Effectiveness and safety of acupuncture and moxibustion for defecation dysfunction after sphincter-preserving surgery for rectal cancer: protocol for systematic review and meta-analysis.

Guixing Xu, Qiwei Xiao, Hanzhou Lei, Yanan Fu, Jing Kong, Qianhua Zheng, Ling Zhao, Fanrong Liang

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guixing Xu *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0002-8040-3656
Qiwei Xiao *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Hanzhou Lei *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yanan FuAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jing KongAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Qianhua ZhengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ling ZhaoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China acuresearch@126.com zhaoling@cdutcm.edu.cn.
Fanrong LiangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China acuresearch@126.com zhaoling@cdutcm.edu.cn.ORCID 0000-0001-8518-9268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDefecation dysfunction (DD) is one of the most common complications following sphincter-preserving surgery for rectal cancer. And there is no effective treatment of DD after sphincter-preserving surgery for rectal cancer. Although some studies suggested that acupuncture and moxibustion (AM) is effective and safe for DD after sphincter-preserving surgery for rectal cancer, lacking strong evidence, for instance, the relevant systematic review, meta-analysis and randomised controlled trial (RCT) of a large, multicentre sample, makes the effects and safety remain uncertain. The present protocol is described for a systematic review and meta-analysis to investigate the effectiveness and safety of AM for DD after sphincter-preserving surgery for rectal cancer. METHODS AND ANALYSIS: We will search nine online databases from inception to 1 October 2019; the language of included trials will not be restricted. This study will include RCTs that performed AM as the main method of the experimental group for patients with DD after sphincter-preserving surgery for rectal cancer. Two of the researchers will independently select the studies, conduct risk of bias assessment and extract the data. We will use the fixed-effects model or random-effects model of RevMan V.5.2 software to analyse data synthesis. The risk ratios with 95% CIs and weighted mean differences or standardised mean differences with 95% CIs will be used to present the data synthesis outcome of dichotomous data respectively and the continuous data. Evidence quality of outcome will be assessed by using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. ETHICS AND DISSEMINATION: Ethical approval is not required in this secondary research evidence, and we will publish the results of this study in a journal or concerned conferences. TRIAL REGISTRATION NUMBER: CRD42019140097.

Indexed as

Acupuncture TherapyMoxibustionRectal NeoplasmsDefecationHumansMeta-Analysis as TopicMulticenter Studies as TopicRandomized Controlled Trials as TopicSystematic Reviews as TopicTreatment Outcomeacupuncture and moxibustiondefecation dysfunctionmeta-analysissphincter preserving surgery for rectal cancersystematic review

Identifiers

PMID32381535
PMCPMC7223156

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.