ArticleBMJ open2020
Copattern of depression and alcohol use in medical care patients: cross-sectional study in Germany.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Association between weekend catch-up sleep and depressive symptoms in young adults: evidence from two national dataset.Scientific reports · 2026Article
- Psychometric network analysis of depression in hypertensive older adults: identifying core symptoms and modifiable risk factors.Frontiers in psychiatry · 2026Article
- Screening Beyond Dependence: At-Risk Drinking and Psychosocial Correlates in the Heart Transplant Population.Diagnostics (Basel, Switzerland) · 2025Article
- Heavy alcohol consumption, depression, their comorbidity and risk of all-cause and cause-specific mortality: a prospective cohort study.Social psychiatry and psychiatric epidemiology · 2025Article
- Examining the cross-sectional relationship of platelet/high-density lipoprotein cholesterol ratio with depressive symptoms in adults in the United States.BMC psychiatry · 2024Article
- Serotonergic dysfunction may mediate the relationship between alcohol consumption and Alzheimer's disease.Pharmacological research · 2024Review
- Association between multimorbidity patterns and incident depression among older adults in Taiwan: the role of social participation.BMC geriatrics · 2023Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo predict depressive symptom severity and presence of major depression along the full alcohol use continuum.
designCross-sectional study.
settingAmbulatory practices and general hospitals from three sites in Germany.
participantsConsecutive patients aged 18-64 years were proactively approached for an anonymous health screening (participation rate=87%, N=12 828). Four continuous alcohol use measures were derived from an expanded Alcohol Use Disorder Identification Test (AUDIT): alcohol consumption in grams per day and occasion, excessive consumption in days per months and the AUDIT sum score. Depressive symptoms were assessed for the worst 2-week period in the last 12 months using the Patient Health Questionnaire (PHQ-8). Negative binomial and logistic regression analyses were used to predict depressive symptom severity (PHQ-8 sum score) and presence of major depression (PHQ-8 sum score≥10) by the alcohol use measures.
resultsAnalyses revealed that depressive symptom severity and presence of major depression were significantly predicted by all alcohol use measures after controlling for sociodemographics and health behaviours (p<0.05). The relationships were curvilinear: lowest depressive symptom severity and odds of major depression were found for alcohol consumptions of 1.1 g/day, 10.5 g/occasion, 1 excessive consumption day/month, and those with an AUDIT score of 2. Higher depressive symptom severity and odds of major depression were found for both abstinence from and higher levels of alcohol consumption. Interaction analyses revealed steeper risk increases in women and younger individuals for most alcohol use measures.
conclusionFindings indicate that alcohol use and depression in medical care patients are associated in a curvilinear manner and that moderation by gender and age is present.
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