Evidence map›Paper›PMID 32381518›Full record

Observational studyArchives of disease in childhood2020

Costs of postoperative morbidity following paediatric cardiac surgery: observational study.

Emma Hudson, Katherine Brown, Christina Pagel, Jo Wray, David Barron, Warren Rodrigues, Serban Stoica, Shane M Tibby, Victor Tsang, Deborah Ridout and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Archives of disease in childhood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emma HudsonDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK eh645@medschl.cam.ac.uk.ORCID 0000-0002-0505-5049
Katherine BrownCardiorespiratory Division, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Christina PagelClinical Operational Research Unit, University College of London, London, UK.ORCID 0000-0002-2857-1628
Jo WrayCardiorespiratory Division, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
David BarronDepartment of Cardiac Surgery, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Warren RodriguesPaediatric Intensive care Unit, NHS Greater Glasgow and Clyde Inverclyde Royal Hospital, Glasgow, UK.
Serban StoicaDepartment of Cardiac Surgery, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Shane M TibbyDepartment of Paediatric Intensive Care, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0001-7774-8656
Victor TsangCardiorespiratory Division, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Deborah RidoutPaediatric Epidemiology Biostatistics, Institute of Child Health, London, UK.
Stephen MorrisDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Funding

Department of Health 12/5005/06
6 · The paper itself

Abstract

objectiveEarly mortality rates for paediatric cardiac surgery have fallen due to advancements in care. Alternative indicators of care quality are needed. Postoperative morbidities are of particular interest. However, while health impacts have been reported, associated costs are unknown. Our objective was to calculate the costs of postoperative morbidities following paediatric cardiac surgery.

designTwo methods of data collection were integrated into the main study: (1) case-matched cohort study of children with and without predetermined morbidities; (2) incidence rates of morbidity, measured prospectively.

settingFive specialist paediatric cardiac surgery centres, accounting for half of UK patients. PATIENTS: Cohort study included 666 children (340 with morbidities). Incidence rates were measured in 3090 consecutive procedures.

methodsRisk-adjusted regression modelling to determine marginal effects of morbidities on per-patient costs. Calculation of costs for hospital providers according to incidence rates. Extrapolation using mandatory audit data to report annual financial burden for the health service. OUTCOME MEASURES: Impact of postoperative morbidities on per-patient costs, hospital costs and UK health service costs.

resultsSeven of the 10 morbidity categories resulted in significant costs, with mean (95% CI) additional costs ranging from £7483 (£3-£17 289) to £66 784 (£40 609-£103 539) per patient. On average all morbidities combined increased hospital costs by 22.3%. Total burden to the UK health service exceeded £21 million each year.

conclusionPostoperative morbidities are associated with a significant financial burden. Our findings could aid clinical teams and hospital providers to account for costs and contextualise quality improvement initiatives.

Indexed as

AdolescentCardiac Surgical ProceduresChildChild, PreschoolCost of IllnessFemaleHeart Defects, CongenitalHospital CostsHumansIncidenceInfantInfant, NewbornMalePostoperative ComplicationsProspective StudiesRegression Analysiscardiac surgerycostinghealth economicshealth servicepaediatric surgery

Identifiers

PMID32381518
PMCPMC7588404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.