Evidence map›Paper›PMID 32381430›Full record

ReviewJournal of dermatological science2020

Cutaneous manifestations of COVID-19: Report of three cases and a review of literature.

Muskaan Sachdeva, Raffaele Gianotti, Monica Shah, Lucia Bradanini, Diego Tosi, Stefano Veraldi, Michael Ziv, Eyal Leshem, Roni P Dodiuk-Gad

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Journal of dermatological science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 9 pooled it
52.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 9 syntheses or guidelines pooled it, 353 citations in OpenAlex.

  1. Pooled it
  2. Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
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  7. COVID-19 and cutaneous manifestations: a systematic review.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
    Pooled it
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  9. SARS-CoV-2 and arbovirus infection: a rapid systematic review.Sao Paulo medical journal = Revista paulista de medicina
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  10. Trichotillomania in long COVID successfully treated with escitalopram: A case report.PCN reports : psychiatry and clinical neurosciences · 2025
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88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Muskaan SachdevaFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Raffaele GianottiInstitute of Dermatological Sciences, University of Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Monica ShahFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Lucia BradaniniDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Italy.
Diego TosiDivision of Infectious Diseases, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital, Milan, Italy.
Stefano VeraldiDepartment of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Michael ZivDermatology Department, Emek Medical Center, Israel.
Eyal LeshemInstitute for Travel and Tropical Medicine, Sheba Medical Centre, Israel; School of Medicine, Tel Aviv University, Israel.
Roni P Dodiuk-GadDermatology Department, Emek Medical Center, Israel; Bruce Rappaport Faculty of Medicine, Technion - Institute of Technology, Israel; Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: rdodiukgad@gmail.com.
University of Toronto · CAASST Fatebenefratelli Sacco · ITEmek Medical Center · ILFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale Maggiore · ITSheba Medical Center · ILUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious cutaneous manifestations have been observed in patients with COVID-19 infection. However, overall similarities in the clinical presentation of these dermatological manifestations have not yet been summarized.

objectiveThis review aims to provide an overview of various cutaneous manifestations in patients with COVID-19 through three case reports and a literature review.

methodsA literature search was conducted using PubMed, OVID, and Google search engines for original and review articles. Studies written in the English language that mentioned cutaneous symptoms and COVID-19 were included.

resultsEighteen articles and three additional cases reported in this paper were included in this review. Of these studies, 6 are case series and 12 are case report studies. The most common cutaneous manifestation of COVID-19 was found to be maculopapular exanthem (morbilliform), presenting in 36.1% (26/72) patients. The other cutaneous manifestations included: a papulovesicular rash (34.7%, 25/72), urticaria (9.7%, 7/72), painful acral red purple papules (15.3%, 11/72) of patients, livedo reticularis lesions (2.8%, 2/72) and petechiae (1.4%, 1/72). Majority of lesions were localized on the trunk (66.7%, 50/72), however, 19.4% (14/72) of patients experienced cutaneous manifestations in the hands and feet. Skin lesion development occurred before the onset of respiratory symptoms or COVID-19 diagnosis in 12.5% (9/72) of the patients, and lesions spontaneously healed in all patients within 10 days. Majority of the studies reported no correlation between COVID-19 severity and skin lesions.

conclusionInfection with COVID-19 may result in dermatological manifestations with various clinical presentations, which may aid in the timely diagnosis of this infection.

Indexed as

AgedAntiviral AgentsBetacoronavirusClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingDisease ProgressionEarly DiagnosisFemaleHumansOxygen Inhalation TherapyPandemicsPneumonia, ViralPredictive Value of TestsSARS-CoV-2Antiviral AgentsCOVID-19Cutaneous manifestationsReviewSkin

Identifiers

PMID32381430
PMCPMC7189855
OpenAlexW3021065458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.