Evidence map›Paper›PMID 32381017›Full record

ArticleBMC veterinary research2020

Live-attenuated Salmonella enterica serotype Choleraesuis vaccine with regulated delayed fur mutation confer protection against Streptococcus suis in mice.

Yu-An Li, Yunyun Chen, Yuan Zhao Du, Weiwei Guo, Dianfeng Chu, Juan Fan, Xiaobo Wang, Matthew Bellefleur, Shifeng Wang, Huoying Shi

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Antibiotic Resistance in Bacteria-A Review.Antibiotics (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Article
  10. Combatting extensively drug-resistantPathogens and global health
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yu-An LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, People's Republic of China.
Yunyun ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, People's Republic of China.
Yuan Zhao DuYebio Bioengineering Co., Ltd of Qingdao, Qingdao, 266114, China.
Weiwei GuoYebio Bioengineering Co., Ltd of Qingdao, Qingdao, 266114, China.
Dianfeng ChuYebio Bioengineering Co., Ltd of Qingdao, Qingdao, 266114, China.
Juan FanYangzhou Uni-Bio Pharmaceutical Co., Ltd, Yangzhou, 225000, Jiangsu, China.
Xiaobo WangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, People's Republic of China.
Matthew BellefleurDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611-0880, USA.
Shifeng WangDepartment of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611-0880, USA.
Huoying ShiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, People's Republic of China. hyshi@yzu.edu.cn.ORCID http://orcid.org/0000-0003-4128-329X
Yangzhou University · CNYebio Bioengineering (China) · CNUniversity of Florida · US

Funding

Jiangsu province and the Priority Academic Program Development of Jiangsu Higher Education Institutions BE2016343National Natural Science Foundation of China 30670079National Natural Science Foundation of China 31172300National Natural Science Foundation of China 31672516Priority Academic Program Development of Jiangsu Higher Education Institutions (CN) PAPDState Key Laboratory of Genetically Engineered Veterinary Vaccines No.AGVSKL-ZD-201807
6 · The paper itself

Abstract

backgroundRecombinant Salmonella enterica serotype Choleraesuis (S. Choleraesuis) vaccine vector could be used to deliver heterologous antigens to prevent and control pig diseases. We have previously shown that a live-attenuated S. Choleraesuis vaccine candidate strain rSC0011 (ΔP

resultsThe strain rSC0012 strain with the ΔP

conclusionsThe live-attenuated Salmonella enterica serotype Choleraesuis vaccine rSC0012(pS-SaoA) with regulated delayed fur mutation provides a foundation for the development of a safe and effective vaccine against S. Choleraesuis and S. suis.

Indexed as

AnimalsFemaleMice, Inbred BALB CMutationSalmonella entericaSalmonella VaccinesSerogroupStreptococcal InfectionsStreptococcus suisVaccines, AttenuatedVaccines, SyntheticSalmonella VaccinesVaccines, AttenuatedVaccines, SyntheticFurImmunogenicityInflammatorySalmonella CholeraesuisVirulence

Identifiers

PMID32381017
PMCPMC7203871
OpenAlexW3023132829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.