Evidence map›Paper›PMID 32380945›Full record

ArticleBMC medical research methodology2020

An assessment of the quality of current clinical meta-analyses.

Irbaz Hameed, Michelle Demetres, Derrick Y Tam, Mohamed Rahouma, Faiza M Khan, Drew N Wright, Keith Mages, Antonio P DeRosa, Becky Baltich Nelson, Kevin Pain and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC medical research methodology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Systematic reviews: Not always a pain.Interventional pain medicine · 2022
    Article
  7. Systematic reviews: Structure, form and content.Journal of perioperative practice · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Irbaz HameedDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA.
Michelle DemetresSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Derrick Y TamSchulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Mohamed RahoumaDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA.
Faiza M KhanDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA.
Drew N WrightSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Keith MagesSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Antonio P DeRosaSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Becky Baltich NelsonSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Kevin PainSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Diana DelgadoSamuel J. Wood Library and C.V. Starr Biomedical Information Centre, Weill Cornell Medicine, New York, NY, USA.
Leonard N GirardiDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA.
Stephen E FremesSchulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.
Mario GaudinoDepartment of Cardiothoracic Surgery, Weill Cornell Medicine, 525 East 68th Street, New York, NY, 10065, USA. mfg9004@med.cornell.edu.ORCID 0000-0003-4680-0815
Cornell University · USSunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to assess the overall quality of study-level meta-analyses in high-ranking journals using commonly employed guidelines and standards for systematic reviews and meta-analyses.

methods100 randomly selected study-level meta-analyses published in ten highest-ranking clinical journals in 2016-2017 were evaluated by medical librarians against 4 assessments using a scale of 0-100: the Peer Review of Electronic Search Strategies (PRESS), Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), Institute of Medicine's (IOM) Standards for Systematic Reviews, and quality items from the Cochrane Handbook. Multiple regression was performed to assess meta-analyses characteristics' associated with quality scores.

resultsThe overall median (interquartile range) scores were: PRESS 62.5(45.8-75.0), PRISMA 92.6(88.9-96.3), IOM 81.3(76.6-85.9), and Cochrane 66.7(50.0-83.3). Involvement of librarians was associated with higher PRESS and IOM scores on multiple regression. Compliance with journal guidelines was associated with higher PRISMA and IOM scores.

conclusionThis study raises concerns regarding the reporting and methodological quality of published MAs in high impact journals Early involvement of information specialists, stipulation of detailed author guidelines, and strict adherence to them may improve quality of published meta-analyses.

Indexed as

Meta-Analysis as TopicResearch ReportHumansMultivariate AnalysisClinicalCochraneEpidemiologyIOMMeta-analysisMethodologyPRESSPRISMAQuality

Identifiers

PMID32380945
PMCPMC7204021
OpenAlexW3022156859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.