Evidence map›Paper›PMID 32380750›Full record

ReviewJournal of clinical medicine2020

Cholangiocarcinoma as an Indication for Liver Transplantation in the Era of Transplant Oncology.

Enrico Gringeri, Martina Gambato, Gonzalo Sapisochin, Tommy Ivanics, Erica Nicola Lynch, Claudia Mescoli, Patrizia Burra, Umberto Cillo, Francesco Paolo Russo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Enrico GringeriHepatobiliary Surgery and Liver Transplantation, Padua University Hospital, 35100 Padua, Italy.ORCID 0000-0002-3459-7306
Martina GambatoMultivisceral Transplant Unit and Gastroenterology, Padua University Hospital, 35100 Padua, Italy.ORCID 0000-0002-0101-1938
Gonzalo SapisochinMulti-Organ Transplant and HPB Surgical Oncology, Division of General Surgery, University Health Network, Department of Surgery, University of Toronto, Toronto, ON M5G 2N2, Canada.
Tommy IvanicsMulti-Organ Transplant and HPB Surgical Oncology, Division of General Surgery, University Health Network, Department of Surgery, University of Toronto, Toronto, ON M5G 2N2, Canada.
Erica Nicola LynchMultivisceral Transplant Unit and Gastroenterology, Padua University Hospital, 35100 Padua, Italy.
Claudia MescoliSurgical Pathology & Cytopathology Unit, Department of Medicine, Padua University Hospital, 35100 Padua, Italy.
Patrizia BurraMultivisceral Transplant Unit and Gastroenterology, Padua University Hospital, 35100 Padua, Italy.ORCID 0000-0002-8791-191X
Umberto CilloHepatobiliary Surgery and Liver Transplantation, Padua University Hospital, 35100 Padua, Italy.
Francesco Paolo RussoMultivisceral Transplant Unit and Gastroenterology, Padua University Hospital, 35100 Padua, Italy.ORCID 0000-0003-4127-8941
University of Padua · ITUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholangiocarcinoma (CCA) arises from the biliary tract epithelium and accounts for 10-15% of all hepatobiliary malignancies. Depending on anatomic location, CCA is classified as intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA). The best treatment option for pCCA is liver resection and when a radical oncological surgery is obtained, 5-year survival rate are around 20-40%. In unresectable patients, following a specific protocol, liver transplantation (LT) for pCCA showed excellent long-term disease-free survival rates. Fewer data are available for iCCA in LT setting. Nevertheless, patients with very early unresectable iCCA appear to achieve excellent outcomes after LT. This review aims to evaluate existing evidence to define the current role of LT in the management of patients with CCA.

Indexed as

cholangiocarcinomaliver transplantationsurgery

Identifiers

PMID32380750
PMCPMC7290472
OpenAlexW3023456580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.