Evidence map›Paper›PMID 32380707›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Bacteriophage Therapy for Critical Infections Related to Cardiothoracic Surgery.

Evgenii Rubalskii, Stefan Ruemke, Christina Salmoukas, Erin C Boyle, Gregor Warnecke, Igor Tudorache, Malakh Shrestha, Jan D Schmitto, Andreas Martens, Sebastian V Rojas and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 2 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 2 syntheses or guidelines pooled it, 137 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pharmacology of Bacteriophage Therapy in Children: A Re-Emerging Paradigm in Antibacterial Therapy.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
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  10. Journal of bacteriology · 2025
    Article
  11. Journal of clinical microbiology · 2025
    Article
  12. Review
  13. Article
  14. [Potential of bacteriophage therapy in Germany: evidence and clinical relevance].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  15. [Phage therapy in Germany-Update 2025].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Evgenii RubalskiiDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Stefan RuemkeDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Christina SalmoukasDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0003-2011-9108
Erin C BoyleDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-5963-3633
Gregor WarneckeDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Igor TudoracheDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Malakh ShresthaDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Jan D SchmittoDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Andreas MartensDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Sebastian V RojasDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Stefan ZiesingInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, 30625 Hannover, Germany.
Svetlana BochkarevaG.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, Moscow 125212, Russia.
Christian KuehnDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Axel HaverichDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DEGabrichevsky Institute of Epidemiology and Microbiology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Objective: Bacterial resistance to conventional antibiotic therapy is an increasingly significant worldwide challenge to human health. The objective is to evaluate whether bacteriophage therapy could complement or be a viable alternative to conventional antibiotic therapy in critical cases of bacterial infection related to cardiothoracic surgery. (2) Methods: Since September 2015, eight patients with multi-drug resistant or especially recalcitrant

Indexed as

bacterial infectioncardiothoracic surgeryimplant-associated infectionphage therapysurgical site infectiontransplant-associated infection

Identifiers

PMID32380707
PMCPMC7277081
OpenAlexW3022234950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.