Evidence map›Paper›PMID 32380640›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Urinary Pharmacokinetic and Pharmacodynamic Profiles of Fosfomycin against Extended-Spectrum β-Lactamase-Producing

Kazuki Harada, Takae Shimizu, Koji Kawaguchi, Takeshi Furuhashi, Genki Ishihara

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kazuki HaradaDepartment of Veterinary Internal Medicine, Tottori University, Tottori 680-8553, Japan.
Takae ShimizuDepartment of Veterinary Internal Medicine, Tottori University, Tottori 680-8553, Japan.
Koji KawaguchiDepartment of Veterinary Internal Medicine, Tottori University, Tottori 680-8553, Japan.
Takeshi FuruhashiAnicom Specialty Medical Institute Inc., Kanagawa 231-0033, Japan.
Genki IshiharaAnicom Specialty Medical Institute Inc., Kanagawa 231-0033, Japan.
Tottori University · JP

Funding

Japan Society for the Promotion of Science 16K18804
6 · The paper itself

Abstract

Fosfomycin is a candidate drug for extended-spectrum β-lactamase (ESBL)-producing bacteria, but its efficacy is yet to be investigated in dogs. This study investigated the urinary pharmacokinetic/pharmacodynamic (PK/PD) profile of fosfomycin orally administered at 80 mg/kg to six healthy dogs to assess its efficacy for canine urinary tract infections (UTIs) caused by ESBL-producing bacteria. Four strains of ESBL-producing

Indexed as

dogsextended-spectrum β-lactamase-producing bacteriaex vivo modelfosfomycinurinary tract infection

Identifiers

PMID32380640
PMCPMC7277591
OpenAlexW3023468496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.