Evidence map›Paper›PMID 32380082›Full record

ArticleThe American journal of pathology2020

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

Brian S Robinson, Bejan Saeedi, Connie M Arthur, Josh Owens, Crystal Naudin, Nourine Ahmed, Liping Luo, Rheinallt Jones, Andrew Neish, Sean R Stowell

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Susceptibility of mice to primaryFrontiers in immunology · 2026
    Article
  6. Review
  7. Murine Models of Transfusion-Induced Red Blood Cell Alloimmunization.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  8. Review
  9. Review
  10. Review
  11. Dichotomous effects of Galectin-9 in disease modulation in murine models of inflammatory bowel disease.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Article
  12. Role of Galectin-1 in the Pathogenesis of Melanoma.Journal of cancer science and clinical therapeutics · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Brian S RobinsonDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
Bejan SaeediDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
Connie M ArthurCenter for Transfusion and Cellular Therapies, Emory University School of Medicine, Atlanta, Georgia.
Josh OwensDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Crystal NaudinDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Nourine AhmedCenter for Transfusion and Cellular Therapies, Emory University School of Medicine, Atlanta, Georgia.
Liping LuoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Rheinallt JonesDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.
Andrew NeishDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia. Electronic address: aneish@emory.edu.
Sean R StowellDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia; Center for Transfusion and Cellular Therapies, Emory University School of Medicine, Atlanta, Georgia. Electronic address: srstowe@emory.edu.
Emory University · US

Funding

Microbial Influence on Mucosal HomeostasisR01AI064462 · NIAID · EMORY UNIVERSITY · PI NEISH, ANDREW S · 2006 to 2022
$5.5M
Research Training in Translational Gastroenterology and HepatologyT32DK108735 · NIDDK · EMORY UNIVERSITY · PI SUBRA KUGATHASAN · 2016 to 2026
$2.6M
Examination of Innate Immunity Against Molecular MimicryDP5OD019892 · OD · EMORY UNIVERSITY · PI STOWELL, SEAN R · 2014 to 2018
$2.2M
Integrating microbial glycan arrays with genomic sequences to study host microbe interactionsU01CA242109 · NCI · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D, STOWELL, SEAN R · 2019 to 2021
$1.5M
NCI NIH HHS U01 CA242109NIAID NIH HHS R01 AI064462NIDDK NIH HHS T32 DK108735NIH HHS DP5 OD019892Wellcome Trust
6 · The paper itself

Abstract

Increasingly, the ß-galactoside binding lectins, termed galectins, are being recognized as critical regulators of cell function and organismal homeostasis. Within the context of the mucosal surface, galectins are established regulators of innate and adaptive immune responses, microbial populations, and several critical epithelial functions, including cell migration, proliferation, and response to injury. However, given their complex tissue distribution and expression patterns, their role within specific processes remains poorly understood. We took a genetic approach to understand the role of endogenous galectin-9 (Gal-9), a mucosal galectin that has been linked to inflammatory bowel disease, within the context of the murine intestine. Gal-9-deficient (Gal9

Indexed as

AnimalsCell MovementCell ProliferationColitisColonGalectinsHumansIntestinal MucosaMiceMice, Knockoutgalectin 9, mouseGalectins

Identifiers

PMID32380082
PMCPMC7416073
OpenAlexW3023462570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.