Evidence map›Paper›PMID 32379300›Full record

ReviewBiochemical Society transactions2020

Biomolecular complex viewed by dynamic nuclear polarization solid-state NMR spectroscopy.

Arnab Chakraborty, Fabien Deligey, Jenny Quach, Frederic Mentink-Vigier, Ping Wang, Tuo Wang

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Comparative Analysis of Polysaccharide and Cell Wall Structure inbioRxiv : the preprint server for biology · 2024
    Article
  5. Review
  6. Solid-state NMR molecular snapshots ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Structure ofBiomacromolecules · 2022
    Article
  8. Review
  9. Structural Elucidation and Activities ofFrontiers in nutrition · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arnab ChakrabortyDepartment of Chemistry, Louisiana State University, Baton Rouge, LA 70803, U.S.A.
Fabien DeligeyDepartment of Chemistry, Louisiana State University, Baton Rouge, LA 70803, U.S.A.
Jenny QuachDepartment of Chemistry, Louisiana State University, Baton Rouge, LA 70803, U.S.A.
Frederic Mentink-VigierNational High Magnetic Field Laboratory, Tallahassee, FL 32310, U.S.A.
Ping WangDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
Tuo WangDepartment of Chemistry, Louisiana State University, Baton Rouge, LA 70803, U.S.A.

Funding

TR&D3-SCHP41GM122698 · NIGMS · FLORIDA STATE UNIVERSITY · PI BREY, WILLIAM W, CROSS, TIMOTHY A · 2017 to 2021
$6.7M
Using Solid-State NMR Spectroscopy to Elucidate Cell Wall Structural Dynamics Involved in Virulence and Drug Response of Aspergillus fumigatusR21AI149289 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI WANG, PING, WANG, TUO · 2020 to 2021
$414k
NIAID NIH HHS R21 AI149289NIGMS NIH HHS P41 GM122698
6 · The paper itself

Abstract

Solid-state nuclear magnetic resonance (ssNMR) is an indispensable tool for elucidating the structure and dynamics of insoluble and non-crystalline biomolecules. The recent advances in the sensitivity-enhancing technique magic-angle spinning dynamic nuclear polarization (MAS-DNP) have substantially expanded the territory of ssNMR investigations and enabled the detection of polymer interfaces in a cellular environment. This article highlights the emerging MAS-DNP approaches and their applications to the analysis of biomolecular composites and intact cells to determine the folding pathway and ligand binding of proteins, the structural polymorphism of low-populated biopolymers, as well as the physical interactions between carbohydrates, proteins, and lignin. These structural features provide an atomic-level understanding of many cellular processes, promoting the development of better biomaterials and inhibitors. It is anticipated that the capabilities of MAS-DNP in biomolecular and biomaterial research will be further enlarged by the rapid development of instrumentation and methodology.

Indexed as

Nuclear Magnetic Resonance, BiomolecularBacteriaBiopolymersCell MembraneCell NucleusCell WallFungiHumansLigandsMembrane ProteinsPlantsPolysaccharidesProtein BindingTemperatureBiopolymersLigandsMembrane ProteinsPolysaccharidescell walldynamic nuclear polarizationmembrane proteinspathogenic fungipolysaccharidessolid-state NMR

Identifiers

PMID32379300
PMCPMC7565284

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.