ArticleThe Journal of bone and joint surgery. American volume2020
Characteristics and Early Prognosis of COVID-19 Infection in Fracture Patients.
Article in The Journal of bone and joint surgery. American volume, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 6 of them syntheses that pooled it.
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Who cites it
139 citing papers in PubMed, 6 syntheses or guidelines pooled it, 227 citations in OpenAlex.
- Mortality in COVID-19 patients after proximal femur fracture surgery: a systematic review and meta-analysis.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2023Pooled it
- Central nervous system manifestations in COVID-19 patients: A systematic review and meta-analysis.Brain and behavior · 2021Pooled it
- Is liver involvement overestimated in COVID-19 patients? A meta-analysis.International journal of medical sciences · 2021Pooled it
- Recommendations of protective measures for orthopedic surgeons during COVID-19 pandemic.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Neurological and Musculoskeletal Features of COVID-19: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2020Pooled it
- [COVID-19 and fragility hip fracture. Joint recommendations of the Spanish Society of Osteoporotic Fractures and the Spanish Society of Geriatrics and Gerontology].Revista espanola de geriatria y gerontologiaGuideline
- Lasting Shifts in Musculoskeletal Injuries Across Pre-, During-, and Post-Pandemic Periods: A Propensity Score-Matched Study.Journal of clinical medicine · 2026Article
- Multiscale bone remodeling in COVID-19: from osteoimmune signaling to structural and mechanical impairment.Frontiers in bioengineering and biotechnology · 2026Review
- Sexual Dimorphism in Systemic Inflammatory Responses to Femur Fracture in Mice Infected With SARS-CoV-2-Like Virus.Journal of medical virology · 2025Article
- Increased complications of proximal femur fractures during the COVID-19 pandemic: a nationwide medical claims database study in Japan.Journal of bone and mineral metabolism · 2025Article
- Association of COVID-19 with thyroid dysfunction and autoimmune thyroid disease: A retrospective cohort study.Journal of translational autoimmunity · 2024Article
- Occupational exposure protection and perioperative management of sudden infectious diseases from the perspective of COVID-19.The Journal of international medical research · 2024Review
- Postoperative Outcomes After Emergency Surgery in COVID-19 Patients: An Ambispective Matched Cohort Study.Cureus · 2024Article
- Article
- COVID-19 hip fracture outcomes: The role of Ct values and D-dimer levels?Journal of orthopaedic translation · 2023Article
- Retrospective Analysis of Nosocomial SARS-CoV-2 Infections in Orthopedic and Traumatological Inpatients.Healthcare (Basel, Switzerland) · 2023Article
- Improving fragility hip fracture care through data: a multicentre experience from a country with an emerging economy during the COVID-19 pandemic.BMJ open quality · 2023Article
- Effects of the COVID-19 Pandemic on Humeral Shaft Fracture Management and Its Outcomes.Cureus · 2023Article
- [The proximal femur fracture epidemic continued during the COVID-19 pandemic: Results of an observational study].Revue de chirurgie orthopedique et traumatologique · 2023Article
- Prevalence and Impact of Gastrointestinal Manifestations in COVID-19 Patients: A Systematic Review.Journal of community hospital internal medicine perspectives · 2023Article
79 more citing papers are in PubMed but not listed here.
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6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies of the novel coronavirus-induced disease COVID-19 in Wuhan, China, have elucidated the epidemiological and clinical characteristics of this disease in the general population. The present investigation summarizes the clinical characteristics and early prognosis of COVID-19 infection in a cohort of patients with fractures.
methodsData on 10 patients with a fracture and COVID-19 were collected from 8 different hospitals located in the Hubei province from January 1, 2020, to February 27, 2020. Analyses of early prognosis were based on clinical outcomes and trends in laboratory results during treatment.
resultsAll 10 patients presented with limited activity related to the fracture. The most common signs were fever, cough, and fatigue at the time of presentation (7 patients each). Other, less common signs included sore throat (4 patients), dyspnea (5 patients), chest pain (1 patient), nasal congestion (1 patient), headache (1 patient), dizziness (3 patients), abdominal pain (1 patient), and vomiting (1 patient). Lymphopenia (<1.0 × 10 cells/L) was identified in 6 of 10 patients, 9 of 9 patients had a high serum level of D-dimer, and 9 of 9 patients had a high level of C-reactive protein. Three patients underwent surgery, whereas the others were managed nonoperatively because of their compromised status. Four patients died on day 8 (3 patients) or day 14 (1 patient) after admission. The clinical outcomes for the surviving patients are not yet determined.
conclusionsThe clinical characteristics and early prognosis of COVID-19 in patients with fracture tended to be more severe than those reported for adult patients with COVID-19 without fracture. This finding may be related to the duration between the development of symptoms and presentation. Surgical treatment should be carried out cautiously or nonoperative care should be chosen for patients with fracture in COVID-19-affected areas, especially older individuals with intertrochanteric fractures. LEVEL OF EVIDENCE: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
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