Evidence map›Paper›PMID 32379047›Full record

ArticleeLife2020

Essential function of the alveolin network in the subpellicular microtubules and conoid assembly in

Nicolò Tosetti, Nicolas Dos Santos Pacheco, Eloïse Bertiaux, Bohumil Maco, Lorène Bournonville, Virginie Hamel, Paul Guichard, Dominique Soldati-Favre

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 122 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Two anchoring proteins control daughter apical complex assembly inbioRxiv : the preprint server for biology · 2026
    Article
  7. Microtubule inner proteins in apicomplexan parasites.Biochemical Society transactions · 2026
    Review
  8. Article
  9. A divergentResearch square · 2025
    Article
  10. Review
  11. mBio · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Architecture of theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nicolò TosettiDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Nicolas Dos Santos PachecoDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-1959-194X
Eloïse BertiauxDepartment of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland.
Bohumil MacoDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Lorène BournonvilleDepartment of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland.
Virginie HamelDepartment of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland.
Paul GuichardDepartment of Cell Biology, Sciences III, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-0363-1049
Dominique Soldati-FavreDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0003-4156-2109
University of Geneva · CH

Funding

EMBO 284-2019European Research Council ACCENT StG 715289H2020 European Research Council 695596H2020 European Research Council 695596 and 695596Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_185325Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_185325 and PP00P3_187198Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PP00P3_187198
6 · The paper itself

Abstract

The coccidian subgroup of Apicomplexa possesses an apical complex harboring a conoid, made of unique tubulin polymer fibers. This enigmatic organelle extrudes in extracellular invasive parasites and is associated to the apical polar ring (APR). The APR serves as microtubule-organizing center for the 22 subpellicular microtubules (SPMTs) that are linked to a patchwork of flattened vesicles, via an intricate network composed of alveolins. Here, we capitalize on ultrastructure expansion microscopy (U-ExM) to localize the

Indexed as

Cell Adhesion MoleculesCells, CulturedHumansMetalloendopeptidasesMicrotubulesProtozoan ProteinsToxoplasmaTubulinalveolinCell Adhesion MoleculesMetalloendopeptidasesProtozoan ProteinsTubulinapicomplexacoccidiainfectious diseasemicrobiologyToxoplasma gondii

Identifiers

PMID32379047
PMCPMC7228768
OpenAlexW3021567235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.