Evidence map›Paper›PMID 32378457›Full record

ArticleJournal of the American Heart Association2020

Heart Failure Risk Associated With Rheumatoid Arthritis-Related Chronic Inflammation.

Michael J Ahlers, Brandon D Lowery, Eric Farber-Eger, Thomas J Wang, William Bradham, Michelle J Ormseth, Cecilia P Chung, C Michael Stein, Deepak K Gupta

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
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  10. Heart failure in autoimmune rheumatic diseases.Rheumatology international · 2026
    Review
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  20. Prognostic impact of rheumatic diseases in patients with heart failure with mildly reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michael J AhlersVanderbilt University School of Medicine Nashville TN.
Brandon D LoweryVanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC) Vanderbilt University Medical Center Nashville TN.
Eric Farber-EgerVanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC) Vanderbilt University Medical Center Nashville TN.
Thomas J WangVanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC) Vanderbilt University Medical Center Nashville TN.
William BradhamDivision of Cardiovascular Medicine Vanderbilt University Medical Center Nashville TN.
Michelle J OrmsethDivisions of Rheumatology and Clinical Pharmacology Vanderbilt University Medical Center Nashville TN.
Cecilia P ChungDivisions of Rheumatology and Clinical Pharmacology Vanderbilt University Medical Center Nashville TN.
C Michael SteinDivisions of Rheumatology and Clinical Pharmacology Vanderbilt University Medical Center Nashville TN.
Deepak K GuptaVanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC) Vanderbilt University Medical Center Nashville TN.
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Dietary sodium, inflammation, and salt sensitivity of blood pressureR01HL148661 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALLEN, NORRINA BAI, GUPTA, DEEPAK · 2019 to 2022
$3.1M
Tissue Sodium, Inflammation, and Blood Pressure in MESAR01HL133860 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GUPTA, DEEPAK, TITZE, JENS MARC · 2016 to 2019
$2.7M
Comparative Safety of Pain MedicationsR01AR073764 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHUNG, CECILIA PILAR · 2019 to 2023
$2.3M
Salt, Blood Pressure, and InflammationR01HL140145 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STEIN, CHARLES M. · 2018 to 2021
$2.3M
The natriuretic peptide system in African-AmericansK23HL128928 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GUPTA, DEEPAK · 2016 to 2019
$737k
Cardiovascular Risk of Non-Opioid Pain MedicationsI01CX001741 · VA · VETERANS HEALTH ADMINISTRATION · PI CHUNG, CECILIA PILAR · 2020 to 2023
–
Functional impact of HDL transport of microRNA in rheumatoid arthritisIK2CX001269 · VA · VETERANS HEALTH ADMINISTRATION · PI ORMSETH, MICHELLE JANE · 2017 to 2021
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CSRD VA I01 CX001741CSRD VA IK2 CX001269NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NHLBI NIH HHS K23 HL128928NHLBI NIH HHS R01 HL133860NHLBI NIH HHS R01 HL140145NIAMS NIH HHS R01 AR073764
6 · The paper itself

Abstract

Background Inflammation may contribute to incident heart failure (HF). Rheumatoid arthritis (RA), a prototypic inflammatory condition, may serve as a model for understanding inflammation-related HF risk. Methods and Results Using the Vanderbilt University Medical Center electronic health record, we retrospectively identified 9889 patients with RA and 9889 control patients without autoimmune disease matched for age, sex, and race. Prevalent HF at entry into the electronic health record or preceding RA diagnosis was excluded. Incident HF was ascertained using

Indexed as

AdultAgedAntirheumatic AgentsArthritis, RheumatoidBiomarkersC-Reactive ProteinElectronic Health RecordsFemaleHeart FailureHumansIncidenceInflammation MediatorsMagnetic Resonance ImagingMaleMethotrexateMiddle AgedAntirheumatic AgentsARTN protein, humanBiomarkersC-Reactive ProteinInflammation MediatorsMethotrexateNerve Tissue Proteinsbiomarkercardiac magnetic resonance imagingheart failureinflammationrheumatoid arthritis

Identifiers

PMID32378457
PMCPMC7660862
OpenAlexW3023678422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.