ReviewInternational wound journal2020
Pyoderma gangrenosum: From historical perspectives to emerging investigations.
Review in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of biologic therapies in the management of pyoderma gangrenosum: a systematic review.Archives of dermatological research · 2024Pooled it
- Pyoderma Gangrenosum Presenting As Recurrent Vulvar Ulceration in a Nine-Year-Old Girl: A Case Report.Cureus · 2026Article
- Pyoderma Gangrenosum Masquerading as Chronic Infective Ulcers: Two Case Reports Across Age Extremes.Clinical case reports · 2026Article
- Pyoderma gangrenosum: pathogenetic mechanisms and their implications for treatment.Seminars in immunopathology · 2025Review
- [Pyoderma gangrenosum: pathogenesis, diagnosis, and treatment].Dermatologie (Heidelberg, Germany) · 2025Review
- The Changing Landscape of Clinical Research in Pyoderma Gangrenosum.The Journal of investigative dermatology · 2025Article
- Narrative Review: Pyoderma Gangrenosum.Cureus · 2024Review
- Pyoderma Gangrenosum: Treatment Options.Drugs · 2023Review
- Idiopathic recurrent pyoderma gangrenosum with cobalamin deficiency in a 62-year-old male: a case report.Annals of medicine and surgery (2012) · 2023Article
- Article
- Practical aspects of the diagnosis and management of pyoderma gangrenosum.Frontiers in medicine · 2023Review
- Computer-Assisted Differential Diagnosis of Pyoderma Gangrenosum and Venous Ulcers with Deep Neural Networks.Journal of clinical medicine · 2022Article
- [Research advances on the pathogenesis and diagnosis of pyoderma gangrenosum].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Review
- A Case of Recurrent Idiopathic Pyoderma Gangrenosum.Cureus · 2022Article
- Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn's Disease: An Observational Study.Gastroenterology research and practice · 2021Article
- [Targeted therapies in Pyoderma gangrenosum: deciphering pathophysiology and improving disease management].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020Review
- Pyoderma gangrenosum.Nature reviews. Disease primers · 2020Review
- Pyoderma gangrenosum: From historical perspectives to emerging investigations.International wound journal · 2020Review
- Development of Pyoderma Gangrenosum in a Patient with Acquired Reactive Perforating Collagenosis.Case reports in dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyoderma gangrenosum (PG) is a rare disease of unknown aetiology, first described over a century ago. Initially thought to have an infectious cause, and now primarily considered an autoinflammatory condition, PG continues to be poorly understood, commonly misdiagnosed, and difficult to treat. In this review, we discuss the journey of our understanding of PG to date, including first descriptions, challenges with diagnosis, presumed pathogenesis, and treatments used. We highlight major historical landmarks and their importance, explain the rationale behind current investigations, note outstanding gaps in knowledge, and explore the future directions of PG research. We summarise what we have known, what we are working on knowing, and what we have yet to explore about PG, illustrating overall trends to invigorate future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.