Evidence map›Paper›PMID 32378168›Full record

ArticleMolecular biology reports2020

Anticancer and antimetastatic activity of Hypomyces chrysospermus, a cosmopolitan parasite in different human cancer cells.

Miriş Dikmen, Selin Engür Öztürk, Zerrin Cantürk, Göksu Ceylan, Ayşe Betül Karaduman, Mustafa Yamaç

Abstract read
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In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Miriş DikmenFaculty of Pharmacy, Department of Pharmacology, Anadolu University, 26210, Eskisehir, Turkey. mirisd@anadolu.edu.tr.ORCID http://orcid.org/0000-0002-9856-3148
Selin Engür ÖztürkTavas Vocational School of Health Services, Pamukkale University, Denizli, Turkey.
Zerrin CantürkFaculty of Pharmacy, Department of Pharmaceutical Microbiology, Anadolu University, 26210, Eskisehir, Turkey.
Göksu CeylanPublic Health Research and Application Center, Central Immunology Laboratory, Gazi University, Ankara, Turkey.
Ayşe Betül KaradumanDuzen Norwest Laboratories, Kaptanpasa Street, No: 2, Buyukesat District, 06700, Ankara, Turkey.
Mustafa YamaçFaculty of Science and Letters, Department of Biology, Eskisehir Osmangazi University, 26480, Eskisehir, Turkey.
Anadolu University · TREskişehir Osmangazi University · TRGazi University · TRPamukkale University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of microbial natural compounds in drug research is increasing every year and they are used to prevent or treat a variety of diseases. Hypomyces chrysospermus is a cosmopolitan parasite of many Boletaceae members. Since not much work has been conducted to date, this study is undertaken to explore the anticancer effect, including the antiproliferative and antimetastatic activity of Hypomyces chrysospermus. The aim of this study is to determine the antiproliferative and antimetastatic activity of Hypomyces chrysospermus ethyl acetate extract, having antioxidant activity, against A549, Caco2, MCF-7 human cancer and CCD-19 Lu and CCD 841 CoN healthy human cell lines. Firstly, cytotoxic activity was determined by the WST-1 assay. After cell proliferations and anti-metastatic effects were investigated by a real-time cell analysis system (RTCA-DP) and IC

Indexed as

A549 CellsAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsApoptotic Protease-Activating Factor 1BasidiomycotaCaco-2 CellsCell Line, TumorCell MovementCell ProliferationHumansHypocrealesMCF-7 CellsNF-kappa BPlant ExtractsTumor Necrosis Factor-alphaAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsAPAF1 protein, humanApoptotic Protease-Activating Factor 1NF-kappa BPlant ExtractsTumor Necrosis Factor-alphaAnticancerAntimetastaticAntioxidantCell cultureHypomyces chrysospermus

Identifiers

PMID32378168
OpenAlexW3021809452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.