Evidence map›Paper›PMID 32377664›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2020

Influence of Processing Pipeline on Cortical Thickness Measurement.

Shahrzad Kharabian Masouleh, Simon B Eickhoff, Yashar Zeighami, Lindsay B Lewis, Robert Dahnke, Christian Gaser, Francois Chouinard-Decorte, Claude Lepage, Lianne H Scholtens, Felix Hoffstaedter and 5 more

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shahrzad Kharabian MasoulehResearch Centre Jülich, Institute of Neuroscience and Medicine (INM-7: Brain and Behavior), 52425, Jülich, Germany.
Simon B EickhoffResearch Centre Jülich, Institute of Neuroscience and Medicine (INM-7: Brain and Behavior), 52425, Jülich, Germany.
Yashar ZeighamiMontreal Neurological Institute, McGill University, Quebec, H3A 2B4, Canada.
Lindsay B LewisMontreal Neurological Institute, McGill University, Quebec, H3A 2B4, Canada.
Robert DahnkeCenter of Functionally Integrative Neuroscience, Department of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.
Christian GaserDepartment of Psychiatry and Department of Neurology, Jena University Hospital, 07747 Jena, Germany.
Francois Chouinard-DecorteMontreal Neurological Institute, McGill University, Quebec, H3A 2B4, Canada.
Claude LepageMontreal Neurological Institute, McGill University, Quebec, H3A 2B4, Canada.
Lianne H ScholtensConnectome Lab, CTG, CNCR, VU Amsterdam, 1081 Amsterdam, Netherlands.
Felix HoffstaedterResearch Centre Jülich, Institute of Neuroscience and Medicine (INM-7: Brain and Behavior), 52425, Jülich, Germany.
David C GlahnDepartment of Psychiatry, Yale School of Medicine, New Haven, CT 06511, USA.
John BlangeroSouth Texas Diabetes and Obesity Institute and Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX 78520, USA.
Alan C EvansMontreal Neurological Institute, McGill University, Quebec, H3A 2B4, Canada.
Sarah GenonResearch Centre Jülich, Institute of Neuroscience and Medicine (INM-7: Brain and Behavior), 52425, Jülich, Germany.
Sofie L ValkResearch Centre Jülich, Institute of Neuroscience and Medicine (INM-7: Brain and Behavior), 52425, Jülich, Germany.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

In recent years, replicability of neuroscientific findings, specifically those concerning correlates of morphological properties of gray matter (GM), have been subject of major scrutiny. Use of different processing pipelines and differences in their estimates of the macroscale GM may play an important role in this context. To address this issue, here, we investigated the cortical thickness estimates of three widely used pipelines. Based on analyses in two independent large-scale cohorts, we report high levels of within-pipeline reliability of the absolute cortical thickness-estimates and comparable spatial patterns of cortical thickness-estimates across all pipelines. Within each individual, absolute regional thickness differed between pipelines, indicating that in-vivo thickness measurements are only a proxy of actual thickness of the cortex, which shall only be compared within the same software package and thickness estimation technique. However, at group level, cortical thickness-estimates correlated strongly between pipelines, in most brain regions. The smallest between-pipeline correlations were observed in para-limbic areas and insula. These regions also demonstrated the highest interindividual variability and the lowest reliability of cortical thickness-estimates within each pipeline, suggesting that structural variations within these regions should be interpreted with caution.

Indexed as

SoftwareAdultBrain MappingCerebral CortexDatasets as TopicFemaleGray MatterHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleinterindividual variabilityin-vivo cortical thicknessreliabilityreplicabilitysoftware comparison

Identifiers

PMID32377664
PMCPMC7391418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.