Evidence map›Paper›PMID 32377618›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2020

The Variable Effects of NSAIDs on Osteotomy Healing and Opioid Consumption.

Austin Fragomen, Jaehee Suh, Kelsey Matta, Thomas H McCoy, Kamber L Hart, S Robert Rozbruch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Do NSAIDs Really Interfere with Healing after Surgery?Journal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Austin FragomenDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.
Jaehee SuhDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.
Kelsey MattaDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.
Thomas H McCoyDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.
Kamber L HartDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.
S Robert RozbruchDepartment of Clinical Orthopaedics, Weill Medical College of Cornell University, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Limb Lengthening and Complex Reconstruction Service, The Hospital for Special Surgery (Dr. Fragomen and Dr. Rozbruch); Hospital for Special Surgery (Ms. Suh), New York, NY; Geisinger Commonwealth School of Medicine, Scranton, PA (Ms. Matta); Department of Medicine and Psychiatry, Harvard Medical School, Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Dr. McCoy); and Center for Quantitative Health, Simches Research Building, Massachusetts General Hospital and Harvard Medical School (Ms. Hart), Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an effort to fight the opioid epidemic, an NSAID pain protocol was created for osteotomy patients. The study asked if NSAIDs negatively affect bone healing or reduce the need for opioids. Methods: This was a retrospective review of 155 limbs that underwent osteotomy of a long bone with fixation. Patients received an NSAID-free protocol or an NSAID protocol. Time to union and bone healing index were recorded. Results: There was not a significant difference in the time to union ( Conclusions: The use of NSAIDs after osteotomy surgery did not negatively affect bone healing and resulted in a dramatic decrease in narcotic consumption for deformity correction patients. Level of Evidence: Level III retrospective cohort study.

Indexed as

Analgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalHumansMorphineOsteotomyRetrospective StudiesAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalMorphine

Identifiers

PMID32377618
PMCPMC7188274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.