Evidence map›Paper›PMID 32377541›Full record

ReviewJournal of immunology research2020

Emerging Prospects for Nanoparticle-Enabled Cancer Immunotherapy.

Manal Ali Buabeid, El-Shaimaa A Arafa, Ghulam Murtaza

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  3. Article
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  5. Review
  6. Nanomedicine in Lung Cancer Immunotherapy.Frontiers in bioengineering and biotechnology · 2023
    Review
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manal Ali BuabeidDepartment of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman 346, UAE.ORCID https://orcid.org/0000-0002-5519-1698
El-Shaimaa A ArafaDepartment of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman 346, UAE.ORCID https://orcid.org/0000-0002-9034-6624
Ghulam MurtazaDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus 54000, Pakistan.ORCID https://orcid.org/0000-0001-5649-5768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the standards for cancer treatment is cancer immunotherapy which treats both primary and metastasized tumors. Although cancer immunotherapeutics show better outcomes as compared with conventional approaches of cancer treatment, the currently used cancer immunotherapeutics have limited application in delivering cancer antigens to immune cells. Conversely, in solid tumors, tumor microenvironment suppresses the immune system leading to the evasion of anticancer immunity. Some promising attempts have been made to overcome these drawbacks by using different approaches, for instance, the use of biomaterial-based nanoparticles. Accordingly, various studies involving the application of nanoparticles in cancer immunotherapy have been discussed in this review article. This review not only describes the modes of cancer immunotherapy to reveal the importance of nanoparticles in this modality but also narrates nanoparticle-mediated delivery of cancer antigens and therapeutic supplements. Moreover, the impact of nanoparticles on the immunosuppressive behavior of tumor environment has been discussed. The last part of this review deals with cancer immunotherapy using a combination of traditional interventional oncology approach and image-guided local immunotherapy against cancer. According to recent studies, cancer therapy can potentially be improved through nanoparticle-based immunotherapy. In addition, drawbacks associated with the currently used cancer immunotherapeutics can be fixed by using nanoparticles.

Indexed as

AnimalsAntigens, NeoplasmHumansImmunityImmunotherapyNanoparticlesNeoplasmsTumor MicroenvironmentAntigens, Neoplasm

Identifiers

PMID32377541
PMCPMC7199570

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.