Evidence map›Paper›PMID 32377505›Full record

ArticleAnalytical cellular pathology (Amsterdam)2020

Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas.

Didier Meseure, Kinan Drak Alsibai, Sophie Vacher, Rana Hatem, Andre Nicolas, Celine Callens, Florence Lerebours, Ivan Bieche

Open access · goldAbstract read
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Didier MeseurePlatform of Experimental Pathology, Institut Curie, F-75248 Paris, France.ORCID https://orcid.org/0000-0001-6730-6686
Kinan Drak AlsibaiDepartment of Pathology, Cayenne Hospital Center, F-97306 Cayenne, France.
Sophie VacherUnit of Pharmacogenomics, Department of Genetics, Institut Curie, F-75248 Paris, France.
Rana HatemUnit of Pharmacogenomics, Department of Genetics, Institut Curie, F-75248 Paris, France.
Andre NicolasPlatform of Experimental Pathology, Institut Curie, F-75248 Paris, France.
Celine CallensUnit of Pharmacogenomics, Department of Genetics, Institut Curie, F-75248 Paris, France.
Florence LereboursDepartment of Medical Oncology, Institut Curie, Rene Huguenin Hospital, F-92210 Saint-Cloud, France.
Ivan BiecheUnit of Pharmacogenomics, Department of Genetics, Institut Curie, F-75248 Paris, France.
Institut Curie · FRDélégation Paris 5 · FRHôpital René Huguenin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (EGFR) signalling is a highly regulated process with a tight balance between receptor activation and inactivation in invasive breast carcinomas (IBCs) particularly in triple-negative carcinomas (TNC). Clinical trials using anti-EGFR therapies are actually performed although no activating alterations (mutations, amplifications, or rearrangements) of

Indexed as

Adaptor Proteins, Signal TransducingBreast NeoplasmsErbB ReceptorsFatty Acid Binding Protein 3FemaleGene Expression Regulation, NeoplasticHumansMembrane ProteinsNeoplasm InvasivenessNeoplasm ProteinsRNA Processing, Post-TranscriptionalTumor Suppressor ProteinsAdaptor Proteins, Signal TransducingEGFR protein, humanELAPOR1 protein, humanErbB ReceptorsERRFI1 protein, humanFABP3 protein, humanFatty Acid Binding Protein 3Membrane ProteinsNeoplasm ProteinsTumor Suppressor Proteins

Identifiers

PMID32377505
PMCPMC7189325
OpenAlexW3019536871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.