Evidence map›Paper›PMID 32377404›Full record

ArticleBMJ global health2020

The prevalence of noma in northwest Nigeria.

Elise Farley, Modupe Juliana Oyemakinde, Jorien Schuurmans, Cono Ariti, Fatima Saleh, Gloria Uzoigwe, Karla Bil, Bukola Oluyide, Adolphe Fotso, Mohana Amirtharajah and 10 more

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Resurgence of Noma (Cancrum Oris) in Nigeria.The American journal of tropical medicine and hygiene · 2024
    Article
  7. Article
  8. Review
  9. Noma finally recognised as a neglected tropical disease.PLoS neglected tropical diseases · 2024
    Article
  10. Article
  11. Estimation of the Prevalence of Noma in Ethiopia, 2007-2019: A Retrospective Study.The American journal of tropical medicine and hygiene · 2023
    Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Noma staging: a review.Tropical medicine and health · 2022
    Review
  18. Article
  19. Model of care, Noma Children's Hospital, northwest Nigeria.Tropical medicine & international health : TM & IH · 2021
    Article
  20. Noma, a neglected disease: A viewpoint article.PLoS neglected tropical diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 5 countries.

Elise FarleyNoma Children's Hospital, Médecins Sans Frontières, Sokoto, Nigeria.ORCID 0000-0003-4457-4068
Modupe Juliana OyemakindeNoma Children's Hospital, Médecins Sans Frontières, Sokoto, Nigeria.
Jorien SchuurmansNoma Children's Hospital, Médecins Sans Frontières, Sokoto, Nigeria.
Cono AritiCentre for Trials Research, Cardiff University School of Medicine, Cardiff, UK.
Fatima SalehDepartment of Surveillance and Epidemiology, Nigeria Centre for Disease Control, Abuja, Nigeria.
Gloria UzoigweDepartment of Dentistry, Nigerian Ministry of Health, Abuja, Nigeria.
Karla BilOperational Center Amsterdam Headquarters, Médecins Sans Frontières, Amsterdam, The Netherlands.
Bukola OluyideNigeria Mission, Médecins Sans Frontières, Abuja, Nigeria.
Adolphe FotsoNigeria Mission, Médecins Sans Frontières, Abuja, Nigeria.
Mohana AmirtharajahOperational Center Amsterdam Headquarters, Médecins Sans Frontières, Amsterdam, The Netherlands.
Jorieke VynckeManson Unit, Médecins Sans Frontières, London, UK.
Raphael BrechardManson Unit, Médecins Sans Frontières, London, UK.
Adeniyi Semiyu AdetunjiDepartment of Clinical Services, Noma Children's Hospital, Sokoto, Nigeria.
Koert RitmeijerOperational Center Amsterdam Headquarters, Médecins Sans Frontières, Amsterdam, The Netherlands.
Saskia van der KamOperational Center Amsterdam Headquarters, Médecins Sans Frontières, Amsterdam, The Netherlands.
Denise Baratti-MayerService of Plastic, Reconstructive and Aesthetic Surgery, Geneva University Hospitals, Geneva, Switzerland.
Ushma MehtaCentre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, Western Cape, South Africa.
Shafi'u IsahDepartment of Clinical Services, Noma Children's Hospital, Sokoto, Nigeria.
Chikwe IhekweazuDepartment of Surveillance and Epidemiology, Nigeria Centre for Disease Control, Abuja, Nigeria.
Annick LengletOperational Center Amsterdam Headquarters, Médecins Sans Frontières, Amsterdam, The Netherlands.
Médecins Sans Frontières · NLMédecins Sans Frontières‎ · GBNigeria Centre for Disease Control · NGSokoto State University · NGUniversity of Cape Town · ZACardiff University · GBFederal Ministry of Health · NGRadboud University Nijmegen · NLUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Noma, a rapidly progressing infection of the oral cavity, mainly affects children. The true burden is unknown. This study reports estimated noma prevalence in children in northwest Nigeria. Methods: Oral screening was performed on all ≤15 year olds, with caretaker consent, in selected households during this cross-sectional survey. Noma stages were classified using WHO criteria and caretakers answered survey questions. The prevalence of noma was estimated stratified by age group (0-5 and 6-15 years). Factors associated with noma were estimated using logistic regression. Results: A total of 177 clusters, 3499 households and 7122 children were included. In this sample, 4239 (59.8%) were 0-5 years and 3692 (52.1%) were female. Simple gingivitis was identified in 3.1% (n=181; 95% CI 2.6 to 3.8), acute necrotising gingivitis in 0.1% (n=10; CI 0.1 to 0.3) and oedema in 0.05% (n=3; CI 0.02 to 0.2). No cases of late-stage noma were detected. Multivariable analysis in the group aged 0-5 years showed having a well as the drinking water source (adjusted odds ratio (aOR) 2.1; CI 1.2 to 3.6) and being aged 3-5 years (aOR 3.9; CI 2.1 to 7.8) was associated with being a noma case. In 6-15 year olds, being male (aOR 1.5; CI 1.0 to 2.2) was associated with being a noma case and preparing pap once or more per week (aOR 0.4; CI 0.2 to 0.8) was associated with not having noma. We estimated that 129120 (CI 105294 to 1 52 947) individuals <15 years of age would have any stage of noma at the time of the survey within the two states. Most of these cases (93%; n=120 082) would be children with simple gingivitis. Conclusions: Our study identified a high prevalence of children at risk of developing advanced noma. This disease is important but neglected and therefore merits inclusion in the WHO neglected tropical diseases list.

Indexed as

NomaAdolescentChildChild, PreschoolCross-Sectional StudiesFamily CharacteristicsFemaleHumansInfantInfant, NewbornMaleNigeriaPrevalencecross-sectional surveyepidemiologyother infection, disease, disorder, or injurypublic health

Identifiers

PMID32377404
PMCPMC7199707
OpenAlexW3016451362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.