Evidence map›Paper›PMID 32377292›Full record

ArticleOxidative medicine and cellular longevity2020

Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis.

Elena Frigato, Mascia Benedusi, Anna Guiotto, Cristiano Bertolucci, Giuseppe Valacchi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Research Progress of Bioactive Components inMolecules (Basel, Switzerland) · 2024
    Review
  2. Inflammasome involvement in CS-induced damage in HaCaT keratinocytes.In vitro cellular & developmental biology. Animal · 2022
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Elena FrigatoDepartment of Life Sciences and Biotechnology, University of Ferrara, I-44121 Ferrara, Italy.ORCID https://orcid.org/0000-0003-4389-5425
Mascia BenedusiDepartment of Medical and Surgical Sciences, University of Ferrara, I-44121 Ferrara, Italy.ORCID https://orcid.org/0000-0002-4656-8609
Anna GuiottoDepartment of Medical and Surgical Sciences, University of Ferrara, I-44121 Ferrara, Italy.ORCID https://orcid.org/0000-0001-5485-3568
Cristiano BertolucciDepartment of Life Sciences and Biotechnology, University of Ferrara, I-44121 Ferrara, Italy.ORCID https://orcid.org/0000-0003-0252-3107
Giuseppe ValacchiDepartment of Medical and Surgical Sciences, University of Ferrara, I-44121 Ferrara, Italy.ORCID https://orcid.org/0000-0002-8792-0947
University of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian rhythms are biological oscillations that occur with an approximately 24 h period and optimize cellular homeostasis and responses to environmental stimuli. A growing collection of data suggests that chronic circadian disruption caused by novel lifestyle risk factors such as shift work, travel across time zones, or irregular sleep-wake cycles has long-term consequences for human health. Among the multiplicity of physiological systems hypothesized to have a role in the onset of pathologies in case of circadian disruption, there are redox-sensitive defensive pathways and inflammatory machinery. Due to its location and barrier physiological role, the skin is a prototypical tissue to study the influence of environmental insults induced OxInflammation disturbance and circadian system alteration. To better investigate the link among outdoor stressors, OxInflammation, and circadian system, we tested the differential responses of keratinocytes clock synchronized or desynchronized, in an

Indexed as

Cells, CulturedCircadian ClocksHomeostasisHumansInflammationKeratinocytesSkin

Identifiers

PMID32377292
PMCPMC7195654
OpenAlexW3020129178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.